Latest Metabolomics Stories

Weizmann Institute scientists unravel the genetic secrets of a pink tomatoFar Eastern diners are partial to a variety of sweet, pink-skinned tomato. Dr. Asaph Aharoni of the Weizmann Institute's Plant Sciences Department has now revealed the gene that's responsible for producing these pink tomatoes. Aharoni's research focuses on plants' thin, protective outer layers, called cuticles, which are mainly composed of fatty, wax-like substances. In the familiar red tomato, this layer also contains...

NORWOOD, Mass., Jan. 12 /PRNewswire/ -- Molecular Biometrics(®), Inc., a metabolomics company developing novel clinical diagnostic tools for applications in personalized medicine, today announced it has completed a $12.5 million Series B financing. New investor Atlas Venture (Waltham, MA) led the round with participation from existing investors Safeguard Scientifics, Inc. (Wayne, PA), and Oxford Bioscience Partners (Boston, MA). The financing will allow the company to accelerate the...

ST. JOSEPH, Mich., Jan. 12 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today they have been awarded a $336K Phase I SBIR grant from the NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES for creating a novel type of predictive signatures for drug resistance. Under this project GeneGo will develop "regulation signatures" which should overcome many shortcomings of existing methods of molecular diagnostics. For this work GeneGo will utilize its extensive,...

Scientists of Helmholtz Zentrum München led by Professor Karsten Suhre have identified new gene variants associated with disturbances in the lipid metabolism. Some of these common human gene variants are already known to be risk factors for diabetes mellitus. The pathomechanisms of diabetes have intrigued physicians and been the subject of much debate for many decades. These new research results may contribute to a better understanding of the clinical picture of diabetes and its...

Doctors may soon be able to quickly and accurately diagnose the cause of pneumonia-like symptoms by examining the chemicals found in a patient's urine, suggests a new study led by UC Davis biochemist Carolyn Slupsky.Pneumonia is a lung infection that annually sickens millions of people in the United States, resulting in approximately 500,000 hospitalizations and thousands of deaths. A rapid, accurate diagnostic test for pneumonia could save lives by enabling doctors to begin appropriate...

MILFORD, Mass., Dec. 9 /PRNewswire-FirstCall/ -- Waters Corporation (NYSE: WAT) announced today that it has shipped the first units of its ground-breaking SYNAPT(TM) G2 Mass Spectrometer, first introduced at the 2009 American Society of Mass Spectrometry (ASMS) annual conference in Philadelphia in June. The instruments are destined for key academic research centers across Europe, North America and Asia and for global pharmaceutical companies and chemical research laboratories. "SYNAPT G2 is...

Journal of Biological Chemistry identifies a study conducted at the School of Medicine study as an 'exemplary prototype'Case Western Reserve University researchers, from the School of Medicine's Department of Nutrition, discovered two new metabolic pathways by which products of lipid peroxidation and some drugs of abuse, known as 4-hydroxyacids, are metabolized. The pathways were identified by a combination of metabolomics and mass isotopomer analysis. The findings shed new light on the...

Findings validate cancer metabolism as an approach to identify new ways to treat cancer, opens potential for new class of cancer drugs targeting metabolic enzymesAgios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough discovery shows that the mutated form of IDH1 produces a metabolite, 2-hydroxyglutarate (2HG), which may...

NEWTOWN SQUARE, Pa., Nov. 18 /PRNewswire/ -- A panel of osteoarthritis (OA) key opinion leaders has developed a consensus of the optimal exogenous hyaluronic acid (HA) treatment. This consensus was achieved by utilizing what the experts referred to as BioRestorative(TM) Profiling. This profiling examines HAs on the basis of their mimicking the body's natural HA. "BioRestorative(TM)" describes the features of the ideal HA product, based on the treatment goals of symptom relief,...

ST. JOSEPH, Mich., Nov. 16 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today the release of a stand alone search product, Eureka! It provides a simple one-button one-window access to GeneGo's manually curated databases. Users can query the database with gene, protein, compound, drug names, diseases, and processes, pathological or toxic categories in a free text format. The results, ranked based on relevance, will present all categories of information...