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Latest Metabolomics Stories

2012-03-09 02:30:20

Glowing 'Spinach' produces a snapshot of abnormal molecules inside diseased cells, providing clues about how to treat disorders By engineering cells to express a modified RNA called "Spinach," researchers have imaged small-molecule metabolites in living cells and observed how their levels change over time. Metabolites are the products of individual cell metabolism. The ability to measure their rate of production could be used to recognize a cell gone metabolically awry, as in cancer, or...

2012-02-08 12:31:39

A large-scale study analyzing metabolic compounds in rice grains conducted by researchers at the RIKEN Plant Science Center (PSC) and their collaborators has identified 131 rice metabolites and clarified the genetic and environmental factors that influence their production. The findings provide a natural way to bioengineer improved rice grain varieties by selectively increasing production of useful metabolites, boosting the nutritional value of crops. As one of the most important staple...

2012-02-08 06:39:34

(Ivanhoe Newswire)-- When fighting tumors it is essential doctors target the metabolic reactions that fuel their growth. A new study shows that a one-size-fits-all metabolism-specific cancer therapy will not fight every type of cancer. Researchers say that metabolic profiling will be imperative for defining each type of cancer and choosing the best treatment option for a patient. Their evidence comes from observing mice that exhibit how tumors metabolic profiles vary. The variations...

2012-01-30 08:25:18

In a study to the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that take part in various chemical reactions of human body. Many of the studied metabolites are biomarkers for cardiovascular disease or related disorders, thus the loci uncovered may provide valuable insight into the biological processes leading to common diseases. Laboratory tests used in...

2012-01-25 12:51:49

At a time of increasing concern about low vitamin D levels in the world's population and increased use of blood tests for the vitamin, scientists are reporting development of a much-needed reference material to assure that measurements of vitamin D levels are accurate. The report appears in ACS' journal Analytical Chemistry. Karen Phinney and colleagues explain that medical research suggests vitamin D deficiency or insufficiency may be even more common than previously thought and a risk...

2012-01-24 06:30:52

(Ivanhoe Newswire) -- Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Exactly how this pain persists is still unknown, and treatment has been largely ineffective. But a new research is helping doctors understand the pain and fix it! It´s critical and it affects thousands every year, but Gary J. Patti, assistant professor of genetics, chemistry, and medicine at Washington University in St. Louis and research...

2012-01-23 10:28:37

Findings suggest new target for drug development Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective. But a team led by scientists from The Scripps Research Institute, using a new approach known as metabolomics, has now discovered a major clue: dimethylsphingosine (DMS), a small-molecule byproduct of cellular membranes...

2011-12-14 12:01:23

New potential avenues for early disease detection A study led by Research Professor Matej Orešič from VTT Technical Research Centre of Finland suggests that Alzheimer's disease is preceded by a molecular signature indicative of hypoxia and up-regulated pentose phosphate pathway. This indicator can be analyzed as a simple biochemical assay from a serum sample months or even years before the first symptoms of the disease occur. In a healthcare setting, the application...


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blee
  • Color; hue; complexion.
This word is Middle English in origin.
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