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Latest Metaplasticity Stories

2011-11-17 03:38:45

Like a gardener who stakes some plants and weeds out others, the brain is constantly building networks of synapses, while pruning out redundant or unneeded synapses. Researchers at The Jackson Laboratory led by Assistant Professor Zhong-wei Zhang, Ph.D., have discovered a factor in synapse-building, also showing that the building and pruning processes occur independent of each other. Mammals are born with functioning but not-yet-developed brains. After birth, external stimuli and internal...

2011-09-29 09:24:18

Nicolas G. Bazan, MD, Ph.D, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health Sciences Center New Orleans, and David Stark, an MD/Ph.D student working in his lab, have discovered how a key chemical neurotransmitter that interacts with two receptors in the brain promotes either normal function or a disease process -- determining whether brain cells live or die. The work is published and highlighted in the September 28, 2011 issue of the Journal of Neuroscience....

2011-07-07 18:56:06

A person who drinks too much alcohol may be able to perform complicated tasks, such as dancing, carrying on a conversation or even driving a car, but later have no memory of those escapades. These periods of amnesia, commonly known as "blackouts," can last from a few minutes to several hours. Now, at Washington University School of Medicine in St. Louis, neuroscientists have identified the brain cells involved in blackouts and the molecular mechanism that appears to underlie them. They report...

2011-06-23 19:50:10

Strength of synapses prove critical in the process of learning and memory Have a tough time remembering where you put your keys, learning a new language or recalling names at a cocktail party? New research from the Lisman Laboratory points to a molecule that is central to the process by which memories are stored in the brain. A paper published in the June 22 issue of the Journal of Neuroscience describes the new findings. The brain is composed of neurons that communicate with each other...

2010-12-09 07:46:38

(Ivanhoe Newswire) -- Medical researchers have found a so-called "missing link" that explains the interaction between brain state and the neural triggers responsible for learning. The good news : this may potentially opening up new ways of boosting cognitive function in the face of diseases such as Alzheimer's as well as enhancing memory in healthy people. Acetylcholine is released in the brain during learning and is critical for the acquisition of new memories. Its role is to facilitate the...

2009-07-13 10:30:00

In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, the Japanese research group led by Professor Masaki Fukata, Drs. Yuko Fukata and Jun Noritake in National Institute for Physiological Sciences, Japan, found that two types of palmitoylating enzymes finely-tune the location and function of a major synaptic protein, PSD-95, in different ways. They also found that this mechanism contributes to keeping synaptic...

2009-06-24 12:07:23

Scientists have uncovered a novel mechanism linking soluble amyloid ? protein with the synaptic injury and memory loss associated with Alzheimer's disease (AD). The research, published by Cell Press in the June 25 issue of the journal Neuron, provides critical new insight into disease pathogenesis and reveals signaling molecules that may serve as potential additional therapeutic targets for AD.Amyloid ? protein (A?) plays a major pathogenic role in AD, a devastating neurodegenerative disorder...

2009-02-12 14:04:42

U.S.-led research is providing strong support for the idea that one of the key functions of sleep is the consolidation of memories. University of Pennsylvania School of Medicine researchers say although sleep is thought to facilitate memory and learning, the molecular links between sleep and synaptic plasticity aren't well understood. Ocular dominance plasticity -- in which one eye can become dominant if the other eye is blocked -- is a classic model of experience-dependent cortical...

2009-02-12 09:07:03

New research provides strong support for the idea that one of the key functions of sleep is the consolidation of memories. The study, published by Cell Press in the February 12th issue of the journal Neuron, provides fascinating insight into the cellular mechanisms that govern the sleep-dependent consolidation of experiences that occur while we are awake.Although sleep is thought to facilitate memory and learning, the molecular links between sleep and synaptic plasticity are not well...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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