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Last updated on April 19, 2014 at 9:20 EDT

Latest metastases Stories

2014-02-20 04:21:29

WHIPPANY, N.J., Feb. 20, 2014 /PRNewswire/ -- Bayer HealthCare today announced that the company has begun to enroll patients in the COAST trial studying Stivarga(®) (regorafenib) tablets in colorectal cancer (CRC) patients with resected liver metastases. The randomized, double-blind, placebo-controlled Phase III trial is designed to determine the effects of Stivarga as adjuvant treatment following surgical removal of liver metastases.(1) "Patients with more advanced colorectal cancer often...

2013-04-24 16:25:20

Novel approach using Listeria bacteria shows promise against a deadly disease BRONX, N.Y., April 24, 2013 /PRNewswire-USNewswire/-- Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them. The experimental treatment dramatically decreased the number of metastases (cancers that have spread to other parts of the body) in a mouse...

2012-06-03 18:20:43

WAYNE, N.J., June 4, 2012 /PRNewswire/ -- Bayer HealthCare today announced updated data from the pivotal Phase III ALSYMPCA (ALpharadin in SYMptomatic Prostate CAncer) trial for its investigational drug radium-223 dichloride[*] in men with castration-resistant prostate cancer (CRPC) and symptomatic bone metastases.[1] Radium-223 dichloride significantly increased overall survival (HR=0.695, p=0.00007).((1) )The median overall survival (OS) benefit in patients given radium-223 dichloride...

2012-03-06 22:58:42

Blocking of receptor protein prevents the development of breast cancer metastases in mice In particularly aggressive forms of breast cancer, cancer cells can settle in other organs and form metastases there. Once such metastases form, complete recovery is rare. Consequently, it is enormously important to prevent the metastasisation of the breast cancer cells. The success, however, achieved by using existing forms of therapy is limited. Scientists from the Max Planck Institute for Heart and...

2012-02-06 05:00:00

MOSCOW, Feb. 6, 2012 /PRNewswire/ -- Russia's first Leksell Gamma Knife® Perfexion(TM) system has found a home at the renowned N.N. Burdenko Neurosurgical Institute, just a five-minute car ride from Moscow's Red Square. On June 2, 2011, a 59-year-old woman was the first Perfexion patient, receiving Gamma Knife® radiosurgery to treat tumor tissue that remained following open surgery. Now, eight months later, the Institute has treated more than 400 patients on the...

2011-12-10 01:30:29

Results also suggest patients who have stray tumor cells in the blood should receive aggressive treatment, even if imaging shows no metastases The presence of circulating tumor cells in the blood appears to have no relationship to survival in women who have just been diagnosed with inflammatory breast cancer, according to new research from Fox Chase Cancer Center. However, the research shows that these stray tumor cells may signal that the disease has spread to other parts of the body,...

2011-12-07 23:04:14

A novel strategy for fighting cancer targets secondary tumors The proliferation of metastases is often the main cause of complications and death from cancer. For the first time, researchers are looking very closely at the development of these metastases themselves, instead of focusing on the "primary" cancers from which they originated. In doing so, a team from the Swiss Center for Experimental Cancer Research (ISREC), at EPFL, was able to isolate a protein that plays a major role in...

2011-03-30 08:00:00

ATLANTA, March 30, 2011 /PRNewswire/ -- The volume of normal brain tissue exposed to radiation during treatment for multiple metastases appears to depend on which stereotactic radiosurgery system is employed, according to a recent study in the Journal of Neurosurgery(1). Comparing treatment plans developed for use by three different treatment systems for a single patient (already previously treated with Leksell Gamma Knife®), researchers found that Gamma Knife plans would...

2011-02-16 16:50:32

A Massachusetts General Hospital (MGH) study has identified a new role for an important enzyme in preparing lung tissue for the development of metastases. Published in the early edition of Proceedings of the National Academy of Sciences, the report describes how focal adhesion kinase (FAK) is involved in producing areas of vascular leakiness in lung tissue "“ known to be part of the premetastatic process "“ and increases expression of a molecule that attracts cancer cells to...

2010-11-18 12:52:17

Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier "“ a tiny capsule specially designed to pass through cell membranes and deliver its anti-cancer drug to the cancer cell. The blood-brain barrier is formed by a network of closely sealed endothelial cells in the brain's capillaries, and it expresses a high level of proteins that pump foreign molecules away from the...