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Latest Metformin Stories

2014-10-31 08:26:39

New evidence helps guide first line diabetes therapy selection given limited comparative effectiveness data WOONSOCKET, R.I., Oct. 31, 2014 /PRNewswire/ -- New research from CVS Health (NYSE: CVS) finds starting a new diabetes patient on metformin, a generic oral diabetes medicine that helps control blood sugar levels, reduced the need to add on additional treatments to control the condition over time. Although there are many classes of oral diabetes medications, there has...

2014-10-21 08:34:10

RIDGEFIELD, Conn. and INDIANAPOLIS, Oct. 21, 2014 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) has accepted the filing of a New Drug Application (NDA) for empagliflozin plus immediate-release metformin hydrochloride fixed-dose combination, an investigational compound being studied for the treatment of adults with type 2 diabetes (T2D). Empagliflozin plus metformin is part of the Boehringer Ingelheim and Eli Lilly and Company (NYSE: LLY) Diabetes alliance portfolio. "Type 2...

grapefruit
2014-10-10 03:00:14

Provided by Sarah Yang, University of California - Berkeley Fad diets come and go, but might there be something to the ones that involve consuming grapefruit and grapefruit juice? New UC Berkeley research suggests that a closer look at grapefruit juice is warranted. A new study published Wednesday, Oct. 8 in the peer-reviewed journal PLOS ONE, found that mice fed a high-fat diet gained 18 percent less weight when they drank clarified, pulp-free grapefruit juice compared with a control...

2014-09-26 08:25:14

-- Reducing Incidence of Limiting Side Effects Could Increase the Utility of this Effective, Safe and Affordable Therapy -- BROOMFIELD, Colo., Sept. 26, 2014 /PRNewswire/ -- MicroBiome Therapeutics(TM) LLC, (MBT) today reported positive topline results from a proof of concept study testing whether its investigational drug, NM 505, can improve the tolerability of metformin, the first-line therapy for Type 2 diabetes worldwide. NM505 is a combination of metformin and active...

2014-09-11 16:26:05

Results from Phase 2b Clinical Study in Patients with Type 2 Diabetes Provide Evidence that SGLT1 inhibition with LX4211 Provides a Clinically Meaningful Benefit THE WOODLANDS, Texas, Sept. 11, 2014 /PRNewswire/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), announced a publication in the online edition of the American Diabetes Association's journal, Diabetes Care, entitled, "Greater Dose-Ranging Effects on A1C Levels Than on Glucosuria With LX4211, a Dual Inhibitor of Sodium...

prediabetes cancer risk
2014-09-10 06:33:34

April Flowers for redOrbit.com - Your Universe Online Professor Yuli Huang of The First People's Hospital of Shunde, China, worked with a team of researchers to conduct a meta-analysis of studies concerning prediabetes. Their findings, published in Diabetologia, are based on 16 studies and 891,426 participants from around the world. The literature review revealed that people with prediabetes have a 15 percent higher risk of developing cancer — and that the level of risk differs depending...

2014-08-28 12:30:33

No overall statistically significant increased risk of bladder cancer in patients ever exposed to pioglitazone in a completed 10-year epidemiological study OSAKA, Japan, Aug. 28, 2014 /PRNewswire/ -- Takeda Pharmaceutical Company Limited ("Takeda") today announced the completion of the post-marketing commitment and submissions of data from a 10-year epidemiology study to regulatory authorities including the United States (U.S.) Food and Drug Administration (FDA), the European Medicines Agency...

diabetes drug metformin
2014-08-11 04:19:36

April Flowers for redOrbit.com - Your Universe Online A large-scale study from Cardiff University, involving over 180,000 people, reveals that people with Type 2 diabetes can live longer than those without the condition, thanks to a widely prescribed blood glucose control medication. The findings, published in Diabetes, Obesity and Metabolism, suggest that metformin — commonly used to control glucose levels in the body and known for exhibiting anticancer properties — could offer...

2014-08-08 20:22:12

In Phase 3 studies, INVOKANA® plus metformin lowered blood sugar and reduced secondary endpoints of body weight and systolic blood pressure to a greater degree than metformin alone RARITAN, N.J., Aug. 8, 2014 /PRNewswire/ -- Janssen Pharmaceuticals, Inc. announced today the U.S. Food and Drug Administration (FDA) has approved INVOKAMET((TM)), a fixed-dose therapy combining canagliflozin and metformin hydrochloride in a single tablet, for the treatment of adults with type 2 diabetes....

diabetes dynamic duo
2014-08-05 03:30:27

Helmholtz Zentrum München Metformin and SGLT2 inhibitors together reduce the blood sugar levels considerably more effectively than either drug alone. Scientists from the Helmholtz Zentrum München, partner in the German Center for Diabetes Research, report in the journal Diabetes that this is due to a synergetic mechanism. Various active substances in oral antidiabetic agents are frequently combined in the treatment of diabetes in order to achieve an effective reduction in the blood...


Word of the Day
barghest
  • A goblin in English folklore, often appearing in the shape of a large dog and believed to portend imminent death or misfortune.
  • A ghost, wraith, hobgoblin, elf, or spirit.
The origin of 'barghest' is not known, but it may be from perhaps burh-ghest, town-ghost, or German Berg-geist (mountain spirit) or Bär-geist (bear-spirit).
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