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The American College of Physicians (ACP) recommends that clinicians add metformin as the initial drug treatment for most patients with type 2 diabetes when lifestyle modifications such as diet, exercise, and weight loss have failed to adequately improve high blood sugar.
Linagliptin (trade name: Trajenta®) has been approved since August 2011 to improve blood glucose control ("glycaemic control") in adults with type 2 diabetes mellitus whose elevated blood glucose levels are inadequately controlled by diet and exercise.
Having diabetes or being obese after age 60 significantly increases the risk for developing breast cancer.
According to the regulators at the U.S.
- Monstrous in size or character; huge; prodigious; monstrously perverse, savage, cruel, etc.