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Latest Methylation Stories

2011-07-11 11:00:00

Mixed lineage leukemias rely on epigenetic changes to grow and survive; new molecule shows promise for targeting these changes therapeutically BOSTON, July 11, 2011 /PRNewswire-USNewswire/ -- A difficult-to-treat form of childhood leukemia relies on changes in the structure of DNA - so-called epigenetic changes - to wreak genomic havoc within white blood cells, according to one of two studies conducted by a research team at Children's Hospital Boston and Dana-Farber Cancer Institute....

2011-06-30 19:04:02

Results suggest novel approach to developing targeted cancer therapies Scientists at Fox Chase Cancer Center have discovered a new mechanism used by cells in the body to turn on silenced genes. This process is critical in preventing the development of cancer"”suggesting the possibility of new therapies that might target the specific changes underlying the disease. The findings will be published online in the journal Cell on June 30, 2011. The process investigated by Alfonso Bellacosa,...

2011-06-27 14:27:30

Findings reveal chaos in biochemical alterations of cancer cells Using the latest gene sequencing tools to examine so-called epigenetic influences on the DNA makeup of colon cancer, a Johns Hopkins team says its results suggest cancer treatment might eventually be more tolerable and successful if therapies could focus on helping cancer cells get back to normal in addition to strategies for killing them. In a report published June 26 in Nature Genetics, the investigators focused on a...

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2011-06-24 08:05:33

Patented test could offer new tool for crime-scene investigation, personalized medicine Self-conscious about your age? Careful where you spit. UCLA geneticists now can use saliva to reveal how old you are. The June 22 advance online edition of the Public Library of Science (PLoS) ONE publishes the findings, which offer a myriad of potential applications. A newly patented test based on the research, for example, could offer crime-scene investigators a new forensic tool for pinpointing a...

2011-06-23 20:35:01

Tokyo, June 24, 2011 - (JCN Newswire) - Researchers at RIKEN have uncovered a mechanism by which the effects of stress in the fly species Drosophila are inherited epigenetically over many generations through changes to the structure of chromatin, the material that makes up the cell nucleus. Published in the journal Cell, the results highlight the role of the transcription factor dATF-2 in chromatin assembly, marking a major advance in our understanding of non-Mendelian inheritance.Recent...

2011-06-23 07:49:00

GREEN BAY, Wis., June 23, 2011 /PRNewswire/ -- Dr. Ajay Goel, Ph.D., Director of Epigenetics and Cancer Prevention at the Gastrointestinal Research Center at Baylor University Medical Center in Dallas, TX, has announced plans for a series of upcoming studies to continue to unlock the mechanisms by which curcumin prevents cancer via its influence on epigenetic activity. While many people believe there is a strong genetic influence in the development of cancer, Dr. Goel states this is...

2011-06-08 01:34:16

As it turns out, humans aren't the only organisms that turn to caffeine for a pick-me-up. University of Iowa scientists have identified four different bacteria that actually can live on caffeine. One of them, known as Pseudomonas putida CBB5, was found in a flowerbed outside a UI research laboratory. The research team says the discovery -- and the new understanding of how the process works -- could in the future allow scientists to convert waste from leftover coffee, tea and even chocolate...

2011-06-03 12:16:30

Two promising new treatments to aid people with autism have shown effectiveness in pilot studies conducted by an Arizona State University professor and private researchers. Several studies indicate that children with autism often have abnormalities in critical biochemical functions that help maintain health "“ specifically methylation, glutathione, and mitochondrial functions. Methylation turns proteins in the body on and off "“ including DNA and RNA "“ a function that...

2011-06-02 13:39:37

The study may allow finding the unknown origin of metastasis and improving treatments Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show that beings with the same genetics like the twins and cloned animals may have different characteristics and disease due to epigenetic changes. Epigenetics involves chemical signatures that...

2011-05-19 06:56:24

(Ivanhoe Newswire) --Children whose mothers and grandmothers smoked during pregnancy are more likely to suffer from childhood asthma and researchers may have just figured out why. A new study shows changes in a process called DNA methylation, that occurs before birth, may be a root cause. DNA methylation can alter a gene's typical function, and the altered genes can be passed along from parent to child. For this study, researchers observed DNA methylation-related changes in the AXL gene in...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.