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Latest Methylation Stories

Are Genes Our Destiny
2011-09-18 06:30:55

  Salk scientists discover 'hidden' code in DNA evolves more rapidly than genetic code A "hidden" code linked to the DNA of plants allows them to develop and pass down new biological traits far more rapidly than previously thought, according to the findings of a groundbreaking study by researchers at the Salk Institute for Biological Studies. The study, published Sept. 16 in the journal Science, provides the first evidence that an organism's "epigenetic" code - an extra layer of...

2011-09-01 16:46:23

DNA/histone combination, a destination for cell signals, also talks to other proteins Chromatin - the intertwined histone proteins and DNA that make up chromosomes — constantly receives messages that pour in from a cell´s intricate signaling networks: Turn that gene on. Stifle that one. But chromatin also talks back, scientists at The University of Texas MD Anderson Cancer Center report today in the journal Cell, issuing orders affecting a protein that has nothing to do with...

2011-08-16 21:01:41

Medical researchers have discovered a new type of mechanism causing cancer susceptibility, showing that tiny changes in some anti-cancer genes can act as magnets to attract modifying "biochemical tags", effectively switching them off and predisposing families to an increased risk of the disease. The study and its findings are reported in the leading international journal Cancer Cell. The researchers, from the University of New South Wales (UNSW), believe a tiny spelling mistake involving a...

2011-08-10 18:08:19

Mariusz A. Wasik, MD, professor of Pathology and Laboratory Medicine, and Qian Zhang, MD, PhD, research assistant professor, both from the Perelman School of Medicine at the University of Pennsylvania, and their colleagues, found that a cancer-causing fusion protein works by silencing the tumor suppressor gene IL-2R common gamma-chain (IL-2RÃŽ³). The results, which appeared in a recent Proceedings of the National Academy of Sciences, suggest news targets for lymphoma and...

2011-08-08 12:21:25

A new study supports the use of a DNA-based "biomarker" blood test as a complement to the prostate-specific antigen (PSA) test currently offered to screen men for prostate cancer. University of Cincinnati (UC) researchers report their findings online ahead of print in the British Journal of Cancer. Researchers conducted a meta-analysis of existing published data related to DNA methylation in bodily fluids. The goal was to evaluate a specific cancer biomarker"”known as GSTP1"”as a...

2011-07-22 01:34:48

For decades, scientists have known that DNA consists of four basic units -- adenine, guanine, thymine and cytosine. Those four bases have been taught in science textbooks and have formed the basis of the growing knowledge regarding how genes code for life. Yet in recent history, scientists have expanded that list from four to six. Now, with a finding published online in the July 21, 2011, issue of the journal Science, researchers from the UNC School of Medicine have discovered the seventh and...

2011-07-11 11:00:00

Mixed lineage leukemias rely on epigenetic changes to grow and survive; new molecule shows promise for targeting these changes therapeutically BOSTON, July 11, 2011 /PRNewswire-USNewswire/ -- A difficult-to-treat form of childhood leukemia relies on changes in the structure of DNA - so-called epigenetic changes - to wreak genomic havoc within white blood cells, according to one of two studies conducted by a research team at Children's Hospital Boston and Dana-Farber Cancer Institute....

2011-06-30 19:04:02

Results suggest novel approach to developing targeted cancer therapies Scientists at Fox Chase Cancer Center have discovered a new mechanism used by cells in the body to turn on silenced genes. This process is critical in preventing the development of cancer"”suggesting the possibility of new therapies that might target the specific changes underlying the disease. The findings will be published online in the journal Cell on June 30, 2011. The process investigated by Alfonso Bellacosa,...

2011-06-27 14:27:30

Findings reveal chaos in biochemical alterations of cancer cells Using the latest gene sequencing tools to examine so-called epigenetic influences on the DNA makeup of colon cancer, a Johns Hopkins team says its results suggest cancer treatment might eventually be more tolerable and successful if therapies could focus on helping cancer cells get back to normal in addition to strategies for killing them. In a report published June 26 in Nature Genetics, the investigators focused on a...

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2011-06-24 08:05:33

Patented test could offer new tool for crime-scene investigation, personalized medicine Self-conscious about your age? Careful where you spit. UCLA geneticists now can use saliva to reveal how old you are. The June 22 advance online edition of the Public Library of Science (PLoS) ONE publishes the findings, which offer a myriad of potential applications. A newly patented test based on the research, for example, could offer crime-scene investigators a new forensic tool for pinpointing a...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'