Latest Methylation Stories
Researchers from the Boston University School of Medicine (BUSM) have determined how the TGFÎ²-Smad signaling pathway, which is over activated in late-stage cancers, is responsible for the "epigenetic memory" that maintains unique patterns of regulatory DNA hypermethylation causing silencing of critical genes that facilitate breast cancer progression.
Scientists have found what they believe is the "missing link" between heart failure, our genes and our environment.
Epigenetic diagnosis and therapies, a new strategy for treating cancer.
Researchers at the UNC School of Medicine have discovered a protein complex that appears to play a significant role in erasing these epigenetic instructions on sperm DNA, essentially creating a blank slate for the different cell types of a new embryo to develop.
Researchers at Uppsala University and University Children's Hospital in Uppsala have devised powerful new tools for typing cells from children with acute lymphatic leukemia and for prediction of how children with leukemia will respond to chemotherapy.
Biomethylation of arsenic compounds appears to cause oxidative DNA damage and to increase their carcinogenicity.
The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult cells.
The search for the holy grail of regenerative medicineâ€”the ability to "grow back" a perfect body part when one is lost to injury or diseaseâ€”has been under way for years, yet the steps involved in this seemingly magic process are still poorly understood.
Researchers at Duke University Medical Center have uncovered a new genetic signature that correlates strongly with autism and which doesn't involve changes to the DNA sequence itself.
Despite the fact that the human genome sequence lists nearly every single DNA base of the roughly 3 billion bases that make up a human genome, it has remained a biological mystery as to how its function is regulated.