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Latest Methylation Stories

2013-06-18 13:14:30

Methylation refers to a chemical modification of DNA and this modification can occur in millions of positions in the DNA sequence. Until now, scientists believed that this epigenetic phenomenon actively reduced the expression of certain genes. Today, a team of researchers from the University of Geneva (UNIGE), Switzerland, led by Emmanouil Dermitzakis, Louis-Jeantet Professor at the Faculty of Medicine, reveals that this is not always the case and that DNA methylation may play both a passive...

2013-06-13 23:27:32

RiboMed Biotechnologies, Inc. (http://www.ribomed.com), a company that develops epigenetic-based tests that provide improved cancer diagnosis and allow drug therapy to be personalized for the benefit of cancer patients, today announced that it has partnered with researchers at the Austrian Institute of Technology (AIT, Vienna) to commercialize their clinically validated lung cancer DNA methylation biomarkers. Lung cancer is the number-one cause of cancer deaths in both men and women in the...

2013-06-07 12:46:23

Serum DNA analysis allows detection of early disease, say researchers in The Journal of Molecular Diagnostics The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera. This test detected 87% of all stages of colorectal cancer cases (sensitivity) without significant difference between early and advanced...

2013-04-02 10:30:31

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research from C. David Allis' laboratory at Rockefeller University may bring scientists closer to designing cancer therapeutics that can target tumors with pinpoint accuracy. Their findings, published last week in Science Express, follow a recent series of discoveries by several international genome...

2013-03-22 09:31:23

Food and environment can chemically alter your gene function and scientists have identified a gene that is consistently altered in obesity. The gene LY86 was among a group of 100 genes identified as likely contributors to obesity through genome-wide association studies comparing the DNA of thousands of obese and lean individuals, said Dr. Shaoyong Su, genetic epidemiologist at the Medical College of Georgia at Georgia Regents University. Su looked at progressively larger groups of obese...

2013-03-18 11:15:32

At the 28th Annual EAU Congress currently ongoing in Milan until Tuesday, W. Tan and colleagues presented their study on neoadjuvant cisplatin-based chemotherapy which showed that epigenetic changes are potential key drivers in the development of chemo resistance in bladder cancer. Neoadjuvant cisplatin-based chemotherapy is recommended for patients with muscle invasive bladder cancer. Cisplatin-based regimes have similar efficacy with complete response in 30% a survival advantage if 16%...

2013-03-07 23:01:28

Zymo Research, The Epigenetics Company, is changing the way we look at the human genome for markers of disease. With a newly expanded range of epigenetic services, Zymo Research helps scientists identify epigenetic alterations that could prove vital for disease diagnosis, prognosis, and the prediction of response to therapies. Irvine, CA (PRWEB) March 07, 2013 Zymo Research Corporation, a privately held company located in Irvine, California, has recently expanded its range of tools and...

2013-03-07 15:20:25

Salk epigenetic findings may aid in crop production Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production and the study of human diseases. Published March 6 in Nature, the findings show that in addition to genetic diversity found in plants throughout the world, their epigenomic makeup is as varied as the environments in which they are...

2013-02-06 12:20:26

A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine. The study, which appears Feb. 6 in the journal BMC Medicine, is the first in humans to show that paternal obesity may alter a genetic mechanism in the next generation, suggesting that a father's lifestyle factors may be transmitted to his children. "Understanding the risks of the current Western lifestyle on...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.