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Latest MHC class I Stories

2013-11-21 23:28:43

Pure MHC, LLC, a provider of MHC-based diagnostics and therapeutics, and Catalent Pharma Solutions, the global leader in drug development solutions and advanced delivery technologies for pharmaceutical, biologic and consumer health products, today announced the signing of a product development agreement. Somerset, NJ, and Austin, TX (PRWEB) November 21, 2013 Pure MHC, LLC, a provider of MHC-based diagnostics and therapeutics, and Catalent Pharma Solutions, the global leader in drug...

2011-10-03 12:30:51

A central element of the immune system has remained constant through more than 400 million years of evolution, according to new research at National Jewish Health. In the September 29, 2011, online version of the journal Immunity, the researchers report that T-cell receptors from mice continue to function even when pieces of shark, frog and trout receptors are substituted in. The function of the chimeric receptors depends on a few crucial amino acids, found also in humans, that help the...

2011-08-30 11:15:03

Bleeding calf syndrome (bovine neonatal pancytopenia or BNP) affects new born calves resulting in low blood cell counts and depletion of the bone marrow. It first emerged in 2007 and a serious number of cases are reported each year. In affected calves, bone marrow cells which produce platelets are also destroyed. Consequently the calves' blood does not clot and they appear to bleed through undamaged skin. There is evidence that BNP is linked to the use of a particular vaccine against "Bovine...

2011-07-26 08:00:00

ASHBURN, Va., and BURNSVILLE, Minn., July 26, 2011 /PRNewswire/ -- Brainware, Inc., the leading provider of intelligent data capture and enterprise search solutions, and MHC Software, Inc., creators of the innovative MHC Image Express(TM) application and solutions for the streamlined processing of accounts payable, procurement and human resources operations, announced today an agreement that will offer customers Brainware Distiller's unmatched capabilities for line-item data extraction and...

2010-04-20 07:45:24

The findings point to a new drug target for type 1 diabetes and other autoimmune diseases Scientists from The Scripps Research Institute have provided an answer to the 40-year-old mystery of how certain genetic mutations lead to Type 1 diabetes. This new molecular understanding could lead to novel therapies for Type 1 diabetes and other autoimmune diseases. The study was published in an advanced, online issue of the Journal of Clinical Investigation on April 19, 2010, and will appear in the...

2010-03-18 10:13:55

Scientists have identified a mechanism that switches on an extremely important process for the proper functioning and survival of our body's cells. Specifically, the fast-track transportation pathway of 'cargo' to and from the surface of the cell. Defects in this trafficking pathway can have severe consequences, leading to numerous diseases such as high cholesterol, neuropathies, sterility and complications in immune response. Understanding the mechanisms underlying these disorders is crucial...

2009-08-31 09:36:30

Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cytoÂmegalovirus to shut down an antiviral defense (online August 31).Cytomegalovirus, which most people contract at some point in their lives, eludes immune system surveillance by targeting the protein MHC I. When we're sick, MHC I captures bits of viral proteins...

2009-06-08 14:41:27

When female tiger salamanders choose a mate, it turns out that size does matter - tail size that is - and that's not the only factor they weigh.Findings of a Purdue University study show that animals make more complex decisions about choosing mates than once thought. The results of Andrew DeWoody's study, released Monday (June 8) in the journal Molecular Ecology, refute a theory that animals use major histocompatibility complex (MHC) genes as the sole basis for mate choice. Immunologists have...

2009-01-13 11:31:53

A study from a team of researchers led by Dr. Andrew P. Makrigiannis, Director of the Molecular Immunology Research Unit at the IRCM, has identified a new mechanism regulating interferon production. This discovery, co-authored by scientists from the International Medical Center of Japan (Tokyo), the National Cancer Institute at Frederick (Maryland) and the McGill Centre for the Study of Host Resistance, was published on December 22, 2008 in the Journal of Experimental Medicine.The...

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2008-06-19 11:42:16

Researchers unravel complexity of the major histocompatibility complex in tailed amphibians Major Histocompatibility Complex (MHC) genes produce proteins that are crucial in fighting pathogen assault. Researchers from the Jagiellonian University in Krakow and from the Helmholtz Centre for Environmental Research (UFZ) characterized genetic variation and detected more than one MHC class II locus in a tailed amphibian. Unlike mammals, not much has been known until now about the immune defense of...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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