Latest MHC Class II Stories
Connie K. Ho for redOrbit.com – Your Universe Online Observations of the relationship between gluten and T-cells in the immune system have allowed researchers from Monash University to get a better understanding on how celiac disease comes into being. According to the scientists, the disorder impacts a significant part of the population--specifically 1 in 133 people. Due to immune response genes HLA-DQ2 or HLA-DQ8, almost half of the population is susceptible to contracting celiac...
CAMBRIDGE, Mass., Oct. 11, 2012 /PRNewswire/ -- A link between gluten and the immune system has literally been visualized in new research published today in a leading scientific journal, Immunity. The discovery is the collaborative work of research groups in Australia, the Netherlands and ImmusanT Inc. based in Cambridge, Massachusetts, led by Professor Jamie Rossjohn and Dr. Hugh Reid at Monash University, Dr. Bob Anderson of ImmusanT and Professor Frits Koning at the University of...
The findings point to a new drug target for type 1 diabetes and other autoimmune diseasesScientists from The Scripps Research Institute have provided an answer to the 40-year-old mystery of how certain genetic mutations lead to Type 1 diabetes. This new molecular understanding could lead to novel therapies for Type 1 diabetes and other autoimmune diseases.The study was published in an advanced, online issue of the Journal of Clinical Investigation on April 19, 2010, and will appear in the May...
The great physical diversity that evolution has forged in human beings is in evidence wherever we look, but the genes exhibiting the greatest diversity at the DNA level happen to function in a wholly invisible process: immunity. Genes encoding the Human Leukocyte Antigen (HLA) proteins are among the most diverse in the human genome, and scientists have proposed a number of hypotheses to explain why. This week, researchers report new findings that support the idea that the striking diversity...
