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Latest Michael B. A. Oldstone Stories

2013-04-12 13:25:11

The findings suggest a new approach to clearing infections from AIDS to hepatitis Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C. The study, reported in the April 12, 2013 issue of the journal Science, focused on the activity of the body's type 1 interferon (IFN-I) proteins. Since its discovery over 50 years ago,...

2011-01-20 21:58:00

Cells infected by measles virus pull out a heavy weapon in the form of the enzyme ADAR1 Scientists at The Scripps Research Institute have found that a known enzyme in cells protects against measles virus, likely by altering the virus's genetic material, RNA. Cells lacking the enzyme become highly vulnerable to the virus's destructive effects. The enzyme also protects against several other respiratory viruses, including influenza A. "We believe that host cells use this RNA-editing enzyme to...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'