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Latest Michael J. Holtzman Stories

Drugs That Limit Excess Mucus Could Save Lives
2012-11-26 19:53:34

Washington University School of Medicine Respiratory conditions that restrict breathing such as asthma and chronic obstructive pulmonary disease (COPD) are common killers worldwide. But no effective treatments exist to address the major cause of death in these conditions — excess mucus production. "There is good evidence that what kills people with severe COPD or asthma is mucus obstructing the airway," says Michael J. Holtzman, MD, the Selma and Herman Seldin Professor of...

2005-09-28 16:55:55

Bethesda, MD "“ By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. This old protein with a new twist may eventually be used to improve the body's defense against infection. Stat1 is involved in immune responses that are initiated by proteins called interferons. These proteins are produced by the cells of the immune system in response to challenges by foreign...


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  • Color; hue; complexion.
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