Latest Microbicides Stories

A reformulated version of an anti-HIV gel developed for vaginal use was found safe and acceptable by HIV-negative men and women who used it rectally, according to a Phase I clinical trial published today in PLOS ONE. The study, led by researchers with the U.S. National Institutes of Health (NIH)-funded Microbicide Trials Network (MTN), tested a reduced glycerin formulation of tenofovir gel, and has spurred the development of an expanded safety study of the gel, expected to launch later this...

PrEP Strategies Remain Valuable Prevention Tool, says AVAC NEW YORK, March 4, 2013 /PRNewswire-USNewswire/ -- Results from a large-scale HIV prevention trial among African women known as VOICE (Vaginal and Oral Interventions to Control the Epidemic) provide an urgent reminder that products must meet the needs of the people using them. While disappointing, the results lend new urgency and direction to the search for additional safe and effective HIV prevention options for women, AVAC...

A new study shows that a microbicide gel is highly effective in block infection by the AIDS virus in a non-human primate model. In the paper published December 6 in the Open Access journal PLOS Pathogens, Dereuddre-Bosquet and colleagues from the European Combined Highly Active Anti-Retroviral Microbicides (CHAARM) Consortium describe the gel's key ingredient, which are small peptides engineered to present a decoy to bind up the virus and prevent it from entering and infecting the cells of...

Connie K. Ho for redOrbit.com – Your Universe Online Researchers have been delving into new human immunodeficiency virus (HIV) prevention technology. A joint effort by the University of Utah and CONRAD has resulted in the development of an intravaginal ring that can be utilized by women to stop the transmission of HIV through sex. Scientists believe that it is the first product that allows for the vaginal delivery of tenofovir in a long-lasting method. Scientists at the University of...

Study provides first efficacy data on vaginal rings for HIV prevention Population Council scientists have found that a vaginal ring releasing an anti-HIV drug can prevent the transmission of SHIV in macaques. This study provides the first efficacy data on the delivery of a microbicide from a vaginal ring, and indicates strong potential for the success of such rings in women. Microbicides are compounds that can be applied inside the vagina or rectum to protect against sexually transmitted...