Latest Microfilament Stories
The tropical disease malaria is caused by the Plasmodium parasite. For its survival and propagation, Plasmodium requires a protein called actin. Scientists of the Helmholtz Centre for Infection Research (HZI) in Germany used high-resolution structural biology methods to investigate the different versions of this protein in the parasite in high detail.
University of Oregon biochemists have determined how tiny synthetic molecules disrupt an important actin-related molecular machine in cells in one study and, in a second one, the crystal structure of that machine when bound to a natural inhibitor.
Muscle contraction and many other movement processes are controlled by the interplay between myosin and actin filaments.
During the final stage of cell division, a short-lived contractile ring constricts the cellular membrane and eventually separates the dividing cell in two.
Cells on the move reach forward with lamellipodia and filopodia, cytoplasmic sheets and rods supported by branched networks or tight bundles of actin filaments.
A new study in the Journal of General Physiology (www.jgp.org) uses state-of-the-art fluorescence microscopy to provide a striking 3-D picture of how class V myosins (myoV) "walk" along their actin track.
Making use of a new "super resolution" microscope that provides sharp images at extremely small scales, scientists have achieved unprecedented views of the immune system in action.
Every cell in the human body contains a complex system to transport essential cargoes such as proteins and membrane vesicles, from point A to point B.
Most cells rely on structural tethers to position chromosomes in preparation for cell division.
- The act of burning, scorching, or heating to dryness; the state or being thus heated or dried.
- In medicine, cauterization.