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Latest Microglia Stories

2012-03-19 10:15:44

Microglia are the first line defence of the brain and are constantly looking for infections to fight off. Overactive microglia can cause uncontrolled inflammation within the brain, which can in turn lead to neuronal damage. New research published in BioMed Central's open access journal Journal of Neuroinflammation shows that, honokiol (HNK) is able to down-regulate the production of pro-inflammatory cytokines and inflammatory enzymes in activated microglia via Klf4, a protein known to...

2012-03-19 10:10:51

Results emphasize immune component of autism spectrum disorder A paper published online today in Nature describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe symptoms of the childhood disorder, including abnormal breathing and movement, and significantly extended the lifespan of Rett mouse models. Exploring the function of microglia deficient in methyl-CpG binding protein 2 (Mecp2),...

2012-03-15 05:39:01

(Ivanhoe Newswire)– Pill for spinal injury? A new study shows an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury (SCI). Researchers uncover how a new pill that has shown positive results in mice with multiple sclerosis suffering from deterioration of the spinal cord, may help humans. Aside from the initial tissue damage, a great deal of the degradation of the spinal cord in SCI is...

2012-03-13 10:31:19

Results reported in the American Journal of Pathology A new study suggests that administering FTY720, an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury (SCI). The research suggests a possible new avenue to counteract the degeneration of the spinal cord in human SCI. The study will be published in the April 2012 issue of The American Journal of Pathology. Beyond the initial tissue damage,...

2011-12-19 16:22:59

Bone marrow-derived stem cells (BMDCs) have been recognized as a source for transplantation because they can contribute to different cell populations in a variety of organs under both normal and pathological conditions. Many BMDC studies have been aimed at repairing damaged brain tissue or helping to restore lost neural function, with much research focused on BMDC transplants to the cerebellum at the back of the brain. In a recent study, a research team from Spain has found that BMDCs, can...

2011-12-13 15:10:32

Research at Wayne State University, Mayo Clinic and Johns Hopkins offers potential treatment for macular degeneration and retinitis pigmentosa Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, the Mayo Clinic and Johns Hopkins Medicine shows that steroids attached to the dendrimers targeted the damage-causing...

2011-11-28 06:51:33

(Ivanhoe Newswire) — According to a recent study, two proteins conspire to promote a lethal neurological disease. Amyotrophic lateral sclerosis, ALS, also known as Lou Gehrig´s disease, is a neurodegenerative disorder that results in progressing loss of motor function and ultimately death. More than 90 percent of ALS cases have no known genetic cause or family history. However, in some patients, spinal cord cells contain unusual accumulations of a protein called TDP-43....

2011-11-14 23:12:47

Two proteins conspire to promote a lethal neurological disease, according to a study published online this week in the Journal of Experimental Medicine (www.jem.org). Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disorder that results in progressive loss of motor function and ultimately death. More than 90% of ALS cases have no known genetic cause or family history. However, in some patients, spinal cord cells contain unusual...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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