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Last updated on April 18, 2014 at 17:08 EDT

Latest Microglia Stories

2009-06-23 11:04:40

New research which suggests a direct link between smoking and brain damage will be published in the July issue of the Journal of Neurochemistry. Researchers, led by Debapriya Ghosh and Dr Anirban Basu from the Indian National Brain Research Center (NBRC), have found that a compound in tobacco provokes white blood cells in the central nervous system to attack healthy cells, leading to severe neurological damage.The research centers on a compound known as NNK, which is common in tobacco. NNK is...

2009-06-15 12:50:08

The idea that anti-inflammatory drugs might protect people struggling with dementia from Alzheimer's disease has received a blow with the online release of a study of human brain tissue in Acta Neuropathologica.Researchers with the McKnight Brain Institute of the University of Florida, in collaboration with scientists at the University of Frankfurt, Germany, discovered that inflammation of microglia -- an abundant cell type that plays an important supporting role in the brain -- does not...

2009-05-28 15:57:58

U.S. scientists say human immunodeficiency virus drug developers should focus on immune cells called macrophages instead of traditionally targeted T cells. In the largest study of its kind, researchers from the University of Florida and five other institutions said they discovered that in diseased cells, such as cancer cells, that are also infected with HIV, nearly all the virus was packed into macrophages, whose job is to eat invading disease agents. The researchers said they also found that...

2009-04-22 06:45:00

BELGRADE, April 22 /PRNewswire-FirstCall/ - Hard To Treat Diseases (HTDS) www.htdsmedical.com - HTDS chief scientist Dr. Sanja Pekovic provided updates from a recent medical convention held in Antwerpen; Joint Meeting 2009 Anatomische Gesellschaft - Nederlandse Anatomen Vereniging, Antwerpen, 27-30 March 2009. Dr. Pekovic reported on the results of recent positive testing being conducted related to the CNS disorder multiple sclerosis and in suppression of reactive astrogliosis after brain...

2009-04-16 15:29:39

In acute ischemic stroke, the blood supply to the brain is restricted. Initially, brain cells die from lack of oxygen. In addition, ischemia activates harmful inflammatory processes in the affected area of the brain. For the first time, scientists at the Neurology Clinic at Heidelberg University Hospital have shown that certain immune cells in the blood inhibit inflammation after a stroke. These cells are known as regulatory T lymphocytes (Treg). The regulator cytokine Interleukin 10 plays an...

2009-04-06 08:41:09

A better understanding of how inflammation impacts neurodegenerative conditions like Parkinson's disease may one day lead to new and better treatments for these conditions. Researchers from the University of California San Diego and the Salk Institute for Biological Studies are looking at a protein called Nurr 1 that's known to be involved in the generation and maintenance of dopaminergic neurons in the brain. These neurons are the main source for dopamine, which helps control a wide variety...

2009-04-02 13:50:10

A new study in the April 3rd issue of the journal Cell, a Cell Press publication, helps to explain why people who carry mutations in a gene known as Nurr1 develop a rare, inherited form of Parkinson's disease, the most prevalent movement disorder in people over the age of 65.They have found evidence that the gene normally acts to suppress an inflammatory response and, in turn, the production of neurotoxins in the brain. Those neurotoxins can otherwise spawn the damage to dopaminergic neurons...

2009-04-02 12:31:22

Could provide target for therapy to treat Parkinson's disease, other neuro-degenerative diseasesA research team from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla has identified a protein in the brain of mice that protects neurons from excessive inflammation, which can lead to neurodegenerative disorders such as Parkinson's disease. Their study, which identifies the protective function of a protein called Nurr1 and defines...

2009-04-01 09:13:11

Scientists at Columbia University Mailman School of Public Health have discovered that astrocytes, supportive cells in the brain that are not derived from an immune cell lineage, respond to a molecule that mimics a viral infection using cellular machinery similar to that used by classical immune cells in the blood. While scientists have been aware of the capacity of astrocytes to trigger an innate immune response when encountering a foreign agent, this work provides a new understanding of the...

2009-03-16 15:30:00

BELGRADE, March 16 /PRNewswire-FirstCall/ - Hard to Treat Diseases (HTDS) www.htdsmedical.com is pleased to announce that a group of investigators (lead by Professor Mirjana Stojiljkovic) from Department of Neurobiology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Serbia, (IBISS group) introduced a novel therapeutic approach in treatment of multiple sclerosis (MS), a severe, currently incurable, human disease. The effectiveness of this therapy is shown in...