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Latest MicroRNA Stories

2013-05-27 10:46:40

In recent years, microRNAs (miRNAs) and other non-coding RNAs are small molecules that help control the expression of specific proteins. In recent years they have emerged as disease biomarkers. miRNA profiles have been used to establish tissue origin for cancers of unknown primary origin, determine prognosis, monitor therapeutic responses and screen for disease, but clinically tractable, diagnostic methods for monitoring miRNA expression in patient samples are not currently available. In this...

Biologists Show RNA Molecule Protects Stem Cells During Inflammation
2013-05-22 09:37:34

California Institute of Technology When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer. Now, a team of researchers led by biologists at the California Institute of Technology (Caltech) has found that, in mouse models,...

2013-05-08 11:34:58

A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot — and without the unwanted side effects. It´s a bit like the classic thought experiment known as the “tumor problem” formulated by Karl Dunker in 1945 and used frequently in the problem-solving literature: Imagine a person suffers from a...

2013-04-30 13:50:14

Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with each other to affect these outcomes. Their findings appear in the journal PLOS ONE. Researchers try to find molecules called biomarkers that help determine a person´s likelihood of getting a disease or, if they have already been diagnosed, how far the disease has advanced. Genes, transcription...

2013-04-30 10:23:08

-Determining a breast-cancer patient´s prognosis can be difficult because breast tumors contain many genetic differences and there are many subtypes; -This study combined and analyzed large masses of data from 466 cases of the most common type of breast cancer; -The study identified a small group of molecules that might predict breast-cancer prognosis across many subtypes of the disease and at its early stages; -For the first time a prognostic signature in cancer is composed of both...

2013-04-29 20:50:00

Neurons in the nose could be the key to early, fast, and accurate diagnosis, says a TAU researcher A debilitating mental illness, schizophrenia can be difficult to diagnose. Because physiological evidence confirming the disease can only be gathered from the brain during an autopsy, mental health professionals have had to rely on a battery of psychological evaluations to diagnose their patients. Now, Dr. Noam Shomron and Prof. Ruth Navon of Tel Aviv University's Sackler Faculty of...

2013-04-23 14:34:19

Researchers at the University of Bonn decode a kind of trigger switch for the conversion of fat cells For a long time, scientists have dreamt of converting undesirable white fat cells into brown fat cells and thus simply have excess pounds melt away. Researchers at the University of Bonn have now gotten a step closer to this goal: They decoded a "toggle switch" in mice which can significantly stimulate fat burning. The results are now being presented in the scientifc journal "Nature...

2013-04-19 17:52:23

An international research team including Christian Schlötterer and Alistair McGregor of the Vetmeduni Vienna has discovered a completely new mechanism by which evolution can change the appearance of an organism.  The researchers found that the number of hairs on flies´ legs varies according to the level of activity of a so-called microRNA.  The results, published in the journal Current Biology, shed a completely new light on the molecular mechanisms of evolution....


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'