Latest MicroRNA Stories

Variations in microRNA expression can lead to sampling bias, according to new study published in the Journal of Molecular Diagnostics Certain short strands of RNA, known as microRNAs (miRNAs), have been linked to the progression and metastasis of breast cancer and may provide information about prognosis. However, studies of miRNA expression profiles often report conflicting findings. While the potential for using miRNAs in breast cancer diagnosis is promising, scientists report in a new...

Researchers and doctors at the North Shore-LIJ Health System and the Feinstein Institute for Medical Research have discovered a potential explanation for why breast cancer is not experienced the same way with African American and Caucasian patients. Chicago, IL (PRWEB) June 02, 2012 Researchers and doctors at the North Shore-LIJ Health System and the Feinstein Institute for Medical Research have discovered a potential explanation for why breast cancer is not experienced the same way with...

LONDON, May 23, 2012 /PRNewswire/ -- A number of large pharmaceutical and biotech companies are keen to invest in life science research. Advances in genomic technologies and molecular biology segments will boost the microRNA (miRNA) research and tools market in the future. MicroRNA is set to unveil a new era in molecular diagnostics and in the development of effective therapeutics. New analysis from Frost & Sullivan (http://www.drugdiscovery.frost.com), Analysis of MicroRNA...

A study has identified microRNA-3151 as a new independent prognostic marker in certain patients with acute leukemia. The study involves patients with acute myeloid leukemia and normal-looking chromosomes(CN-AML). The study by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) found that when microRNA-3151 (miR-3151) is overexpressed in CN-AML, the disease responds poorly to...

Sanford-Burnham researchers develop a method called miR-TRAP, which allows scientists to better understand the roles microRNAs play in human development and disease Human cells are thought to produce thousands of different microRNAs (miRNAs)—small pieces of genetic material that help determine which genes are turned on or off at a given time. miRNAs are an important part of normal cellular function, but they can also contribute to human disease—some are elevated in certain tumors, for...

BELMONT, Calif., May 8, 2012 /PRNewswire/ -- Phalanx Biotech Group, a global genomic products and service provider, announces today the completion of manufacturing and testing for a proprietary targeted chromosomal microarray (CMA) designed specifically for prenatal and postnatal detection of microdeletions and microduplications related to a spectrum of congenital disorders, especially developmental and intellectual delay disorders. CytoOneArray® is capable of detecting 264...

LA JOLLA, Calif., April 30, 2012 /PRNewswire/ -- Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today the appointment of Bruce Carter, Ph.D. to its Board of Directors. Dr. Carter currently serves as an independent member of the Board of Directors of Immune Design Corp., a privately held biotech company located in Seattle, and as a board member of additional scientific organizations....

Novel regulatory molecules called mirror-microRNAs control multiple aspects of brain function Our genes control many aspects of who we are — from the colour of our hair to our vulnerability to certain diseases — but how are the genes, and consequently the proteins they make themselves controlled? Researchers have discovered a new group of molecules which control some of the fundamental processes behind memory function and may hold the key to developing new therapies for treating...

Scientists at Duke University Medical Center have shown the ability to turn scar tissue that forms after a heart attack into heart muscle cells using a new process that eliminates the need for stem cell transplant. The study, published online April 26 in the journal Circulation Research, used molecules called microRNAs to trigger the cardiac tissue conversion in a lab dish and, for the first time, in a living mouse, demonstrating the potential of a simpler process for tissue regeneration....

For the first time, researchers have converted scar tissue that forms after a heart attack into regenerated heart muscle using microRNA, according to an animal study reported in Circulation Research, an American Heart Association journal. After a heart attack, heart muscle doesn't easily regenerate and it accumulates scar tissue, made up of cells called fibroblasts — increasing risk for heart failure. "Researchers have tried various approaches, including the use of stem cells, to...