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Last updated on April 16, 2014 at 1:21 EDT

Latest MicroRNA Stories

2013-07-24 04:22:21

Patent covers methods of detecting cell-free microRNA in urine and blood SAN DIEGO, July 24, 2013 /PRNewswire/ -- Trovagene, Inc. (NASDAQ: TROV), a developer of cell-free molecular diagnostics, announced the issuance of US patent 8,486,626, "Methods of detecting cell-free miRNA in urine and blood." The patent pertains to the detection and quantitation of microRNA (miRNA) using a wide variety of technologies and platforms. MicroRNAs are known to play critical roles in cell development...

2013-07-19 15:37:35

UC San Francisco researchers have found a way to knock down cancers caused by a tumor-driving protein called “myc,” paving the way for patients with myc-driven cancers to enroll in clinical trials for experimental treatments. Myc acts somewhat like a master switch within cells to foster uncontrolled growth. Until now, it has been impossible to target with drugs. The discovery of an unexpected biochemical link within tumor cells should lead to clinical...

RNA Stores More Functional Genome Data Than Previously Thought
2013-07-12 04:51:08

redOrbit Staff & Wire Reports - Your Universe Online Contrary to the belief that a large percentage of the human genome contains "junk" material, a team of Australian scientists report they have discovered an unexpectedly high proportion of functional elements that have been conserved through evolution. According to Dr. Martin Smith and Professor John Mattick of the Garvan Institute of Medical Research in Sydney, less than 1.5 percent of the human genome is devoted to conventional...

2013-07-01 15:04:38

A team led by scientists at The Scripps Research Institute (TSRI) has identified a family of tiny RNA molecules that work as powerful regulators of the immune response in mammals. Mice who lack these RNA molecules lose their normal infection-fighting ability, whereas mice that overproduce them develop a fatal autoimmune syndrome. "This finding gives us insights into immune regulation that could be very helpful in a range of medical applications, from viral vaccines to treatments for...

2013-06-19 04:21:36

Highly sensitive and accurate test detects cancer-related microRNA in blood of patients even before the development of colorectal cancer DALLAS, June 19, 2013 /PRNewswire-USNewswire/ -- A new blood test developed in the Gastrointestinal Cancer Research Lab at Baylor Research Institute is showing very promising results for finding cancer-related microRNA in the blood before a tumor develops in the colon. (Photo: http://photos.prnewswire.com/prnh/20130619/DC33230) The test results,...

2013-06-06 20:02:51

Structural and molecular differences between human Argonaute proteins reveal essential elements for RNA-slicing Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference. RNAi, as it is often called, is a mechanism that cells use to regulate gene expression. Human Argonaute-2 (hAgo2) is known as "slicer" for its unique ability among the 4 human Argonaute proteins to directly cut messenger RNA -- which carries the information coded in genomic DNA to make a...

2013-06-06 08:30:05

Fifth Validation Study Demonstrating Ability to Identify Tumor Origin in Patients with Cancer of Unknown or Uncertain Primary Shows 92% Accuracy, Highest Published Level to Date PHILADELPHIA and REHOVOT, Israel, June 6, 2013 /PRNewswire/ -- Rosetta Genomics Ltd. (NASDAQ: ROSG), a leading developer and provider of microRNA-based molecular diagnostics, announces that a manuscript reporting data validating the clinical utility of the Rosetta Cancer Origin Test((TM)) (formerly...

2013-06-05 12:31:19

HUNTSVILLE, Ala., June 5, 2013 /PRNewswire/ -- EGEN, Inc., a clinical stage biopharmaceutical company, announced today that EGEN's proprietary lung targeting Staramine-mPEG nanoparticle delivery system has been used to administer an inhibitor of microRNA-145 (anti-miRNA-145) in a rat model of severe occlusive PAH. Treatment was shown to significantly reverse the pulmonary hypertension associated with the advanced stages of the disease and restore cardiovascular function. This program, in...

2013-05-27 10:46:40

In recent years, microRNAs (miRNAs) and other non-coding RNAs are small molecules that help control the expression of specific proteins. In recent years they have emerged as disease biomarkers. miRNA profiles have been used to establish tissue origin for cancers of unknown primary origin, determine prognosis, monitor therapeutic responses and screen for disease, but clinically tractable, diagnostic methods for monitoring miRNA expression in patient samples are not currently available. In this...

Biologists Show RNA Molecule Protects Stem Cells During Inflammation
2013-05-22 09:37:34

California Institute of Technology When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer. Now, a team of researchers led by biologists at the California Institute of Technology (Caltech) has found that, in mouse models,...