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Latest Microtubule Stories

b7397b04554909cffbefe23b1fba209a
2010-09-09 09:10:42

A new University of Georgia study published in the journal Nature  has identified a critical enzyme that keeps traffic flowing in the right direction in the nervous system, and the finding could eventually lead to new treatments for conditions such as Alzheimer's and Parkinson's disease. "There was no medical or any other applied science drive for this project; it was purely curiosity about how transport inside cells works," said study co-author Jacek Gaertig, professor in the cellular...

2010-07-07 15:45:15

Japanese team hopes new discovery will aid in creation of therapies for visual, hearing problems It's safe to say that cilia, the hairlike appendages jutting out from the smooth surfaces of most mammalian cells, have long been misunderstood "“ underestimated, even. Not to be confused with their whiplike cousins flagella, which propel sperm, one type of cilia has been known to serve as microscopic conveyor belts. (Picture cilia reaching up like concertgoers supporting a crowd-surfer.)...

2010-05-14 10:16:25

Whitehead Institute researchers have determined a key part of how cells regulate the chromosome/microtubule interface, which is central to proper chromosomal distribution during cell division. "This is the surveillance machinery that makes sure that the chromosomes are divided correctly between cells," says Whitehead Member Iain Cheeseman. The findings are published in this week's issue of Molecular Cell. During cell division, the cell's DNA is consolidated into X-shaped chromosome pairs that...

52cef5c1ae89b03225890abf0c3620301
2010-04-16 08:53:21

Findings shed light on brain malformation that kills infants A University of Utah researcher helped discover how a "wimpy" protein motor works with two other proteins to gain the strength necessary to move nerve cells and components inside them. The findings shed light on brain development and provide clues to a rare brain disorder that often kills babies within months of birth. "It's like the 'Transformers' films: You start with this puny little car and it becomes a big robot capable of...

34582517d05daebe55988366faa507ce1
2010-02-18 12:55:00

Life's smallest motor, a protein that shuttles cargo within cells and helps cells divide, does so by rocking up and down like a seesaw, according to research conducted by scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory and Brandeis University. The researchers created high-resolution snapshots of a protein motor, called kinesin, as it walked along a microtubule, which are tube-shaped structures that form a cell's "skeleton." The result is the closest look...

2009-12-06 13:51:03

Structurally, functionally different cell component replaces injured part Studies with fruit flies have shown that the specialized nerve cells called neurons can rebuild themselves after injury. These results, potentially relevant to research efforts to improve the treatment of patients with traumatic nerve damage or neurodegenerative disease, were presented at the American Society for Cell Biology (ASCB) 49th Annual Meeting, Dec. 5-9, 2009 in San Diego. An injured neuron's remarkable ability...

d42062ea4ed48874a76c016665932faa1
2009-08-17 16:25:00

"A biologist, a physicist, and a nanotechnologist walk into a ..." sounds like the start of a joke. Instead, it was the start of a collaboration that has helped to decipher a critical, but so far largely unstudied, phase of how cells divide. Errors in cell division can cause mutations that lead to cancer, and this study could shed light on the role of chromosome abnormalities in uncontrolled cell replication.The biologist in question is University of Pennsylvania School of Medicine Associate...

7be48c22c84e34c5e0d37b64a7f42f0b1
2009-08-14 10:00:00

Friction is the force that resists the relative motion of two bodies in contact. The same is true on the nanoscale: Molecular motors have to fight the friction created between them and their tracks. However, since the frictional forces acting on such motors had not been measured before, it was not known how they depend on the speed and the direction of motion.Friction Slows Down ProteinsScientists in Dresden at the Biotechnology Center (BIO-TEC) of the Technical University of Dresden and at...

d39b5823857c5ae37d5475ab1636027b1
2009-06-15 09:55:00

Study shows stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth diseaseStalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology (www.jcb.org). A mutant protein makes the microtubules too stable to perform their jobs, the researchers find.The mutations behind CMT disease slow nerve impulses,...

2009-03-23 08:28:55

U.S. scientists say they are studying motor proteins as possible nanoscale machines for drug delivery inside the body's cells. Pennsylvania State University Associate Professor William Hancock said motor proteins, which transport chromosomes, mitochondria or bundles of proteins within cells, might be used to deliver drugs or even help inhibit tumor growth. Hancock said most motor proteins contain two motor domains, or heads, attached to a shared cargo-binding domain, or tail. Think of it as a...


Latest Microtubule Reference Libraries

Arbacia punctulata
2013-11-06 11:08:03

Arbacia punctulata is a species of Arbacia genus of purple-spined sea urchins. Its natural habitat is in the Western Atlantic Ocean. It can be found in shallow water from Massachusetts to Cuba and the Yucatan Peninsula, from Texas to Florida in the Gulf of Mexico, the coast from Panama to French Guiana and in the Lesser Antilles, normally on sandy, rocky, or shelly bottoms. It is omnivorous, consuming a wide variety of preys. It’s been shown that it is galactolipids, rather than...

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Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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