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Latest Midbrain Stories

2012-03-21 15:19:55

What characterizes many people with depression, schizophrenia and some other mental illnesses is anhedonia: an inability to gain pleasure from normally pleasurable experiences. Exactly why this happens is unclear. But new research led by neuroscientists at the University of North Carolina at Chapel Hill School of Medicine may have literally shined a light on the answer, one that could lead to the discovery of new mental health therapies. A report of the study appears March 22 in the...

2011-12-13 22:52:18

Researchers convert astrocytes directly into dopamine-producing nerve cells of the midbrain In efforts to find new treatments for Parkinson´s Disease (PD), researchers from the Perelman School of Medicine at the University of Pennsylvania have directly reprogrammed astrocytes, the most plentiful cell type in the central nervous system, into dopamine-producing neurons. PD is marked by the degeneration of dopaminergic neurons in the midbrain. Dopamine is a brain chemical important in...

2011-09-07 11:08:41

Emotional balance is regulated by molecular factors behind stress response When healthy people are faced with threatening situations, they react with a suitable behavioral response and do not descend into a state of either panic or indifference, as is the case, for example, with patients who suffer from anxiety. With the help of genetic studies on mice, scientists from the Max Planck Institute of Psychiatry have discovered two opposing neuronal regulatory circuits for the generation and...

2011-05-04 13:10:39

Memory-like effects in brain reward pathway could contribute to drug addiction The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a study published in The Journal of Neuroscience. The results suggest that nicotine and cocaine hijack similar mechanisms of memory on first contact to...

2011-02-23 22:17:39

The lateral habenula is hyperactive in rat models of human depression A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL), Brookhaven National Laboratory (BNL) and UC San Diego (UCSD) has collected evidence suggesting that a previously overlooked portion of the brain could be a prime locus of human depression. In two rat models of human depression, the scientists have demonstrated that neurons in a tiny area in the central brain called the lateral habenula (LHb) are...

2011-02-15 06:00:00

SAN DIEGO, Feb. 15, 2011 /PRNewswire/ -- Ceregene, Inc., a biopharmaceutical company, reported today that its scientists and collaborators have published new experimental findings in support of its Parkinson's disease program which appeared as the lead article in the current issue of Movement Disorders (the official journal of the Movement Disorders Society). The publication reports the first evidence that gene transfer can provide targeted expression of a neurotrophic factor, i.e.,...

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2011-02-11 08:24:31

Investigators Build a Case Linking Chemical DOPAL to Illness In new research from Saint Louis University, investigators have found evidence that a toxin produced by the brain is responsible for the series of cellular events that lead to Parkinson's disease. The study, published in PLoS One, found that the brain toxin DOPAL plays a key role in killing the dopamine neurons which trigger the illness. In earlier research, Saint Louis University investigators found that DOPAL seemed to be...

2011-02-03 08:00:00

SAN DIEGO, Feb. 3, 2011 /PRNewswire/ -- Ceregene, Inc., a biopharmaceutical company, announced today that it is progressing with enrollment and dosing in its CERE-120 (AAV2-neurturin) Phase 2b multi-center, sham-surgery, double-blinded controlled trial in Parkinson's disease. This trial was initiated in October 2010 and all 11 centers across the United States are now actively enrolling patients. These sites are among the best movement disorders centers in the country and include Baylor...

2010-11-10 18:00:08

Exhausted neurons die prematurely and trigger disease symptoms We all know that living a stressful lifestyle can take its toll, making us age faster and making us more susceptible to the cold going around the office. The same appears to be true of neurons in the brain. According to a new Northwestern Medicine study published Nov. 10 in the journal Nature, dopamine-releasing neurons in a region of the brain called the substantia nigra lead a lifestyle that requires lots of energy, creating...


Latest Midbrain Reference Libraries

Midbrain
2013-07-25 15:13:23

The midbrain, also known as the mesencephalon is the part of the brain most responsible for vision, motor control, arousal, temperature regulation, alertness and hearing. Formation and Orientation The midbrain is found under the cerebral cortex and above the hindbrain. The mesencephalon is not divided into any other portions of the brain unlike the other two vesicles that stem from the neural tube. There are four separate lobes on the side of the cerebral aqueduct within the...

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Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'