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Latest Miltefosine Stories

2013-10-08 13:58:05

Relapses after treatment for Leishmania infection may be due to a greater infectivity of the parasite rather than drug resistance, as has been previously thought, according to a study published in mBio®, the online open-access journal of the American Society for Microbiology. Visceral leishmaniasis, also called kala-azar, is a parasitic disease that strikes 400,000 people every year and kills around 1 in 10 of its victims. The disease has proven difficult to treat, in part because a large...

2012-02-03 12:24:36

Researchers at the University of Dundee have identified fexinidazole as a possible, much-needed, new treatment for the parasitic disease visceral leishmaniasis. Leishmaniasis is named after William Leishman, a Glasgwegian doctor serving with the British Army in India, who first identified the parasite in the early 1900s. The disease is the second biggest killer in Africa, Asia and Latin America after malaria, and affects 500,000 people, killing about 50-60,000 patients per year. Current...

2011-12-21 15:03:00

Scientists of the Institute of Tropical Medicine (ITG) discovered a parasite that not only had developed resistance against a common medicine, but at the same time had become better in withstanding the human immune system. With some exaggeration: medical practice helped in developing a superbug. For it appears the battle against the drug also armed the bug better against its host. "To our knowledge it is the first time such a doubly armed organism appears in nature", says researcher Manu...

2010-11-26 00:01:47

Visceral Leishmaniasis program expands to support South Asian regional elimination efforts. San Francisco, CA (PRWEB) November 24, 2010 The Institute for OneWorld Health (iOWH), the US based non-profit pharmaceutical company with offices in San Francisco, USA and India that develops drugs for people with neglected infectious diseases in the developing world, today announced a new program in Nepal and Bangladesh to develop a therapy for Visceral Leishmaniasis (VL) available through a grant...

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2009-12-08 10:10:36

The parasite Trypanosoma cruzi (or T. cruzi), which causes Chagas' disease, will go to great lengths to evade death once it has infected human host cells, researchers have discovered. In a study published in the November 17 online issue of Science Signaling, the researchers describe how a protein called parasite-derived neurotrophic factor (PDNF) prolongs the life of the T. cruzi parasite by activating anti-apoptotic (or anti-cell-death) molecules in the host cell. These protective mechanisms...

2008-12-18 09:44:34

Hundreds of millions of people, mainly in developing countries, are disabled by infectious diseases, according to the World Health Organization.More than 12 million people in 88 countries are infected with leishmaniasis, a parasitic disease spread by the bite of infected sand flies. Nearly 2 million new cases are reported and about 70,000 people die from the disease annually.Researchers at the University of Illinois at Chicago have discovered that compounds derived from a natural product can...

2008-09-25 09:00:15

Dutch doctors uncover medical fraud in Bangladesh BRUSSELS, Sept. 23 (Xinhua) -- Doctors from an Amsterdam hospital have sounded the alarm about a possible fraud related to medication for the potentially fatal infectious disease of leishmaniasis, Dutch paper De Telegraaf reported Tuesday. Two doctors from Amsterdam's Slotervaart Hospital said they had discovered the scam while working in Bangladesh. Hundreds of Bangladeshi patients suffering from leishmaniasis, or black fever, had...

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2008-02-01 00:10:00

Researchers at University of Rochester Medical Center reported yesterday a drug used to treat parasitic infections in developing countries also attacks the human immunodeficiency virus (HIV) in a new and powerful way.Past research has established that HIV has "learned" to hide out in certain human cells where it is safe from the body's counterattack, cells that come to serve as viral reservoirs. Operating from these havens, the virus slowly builds its numbers over more than a decade until it...

2008-01-31 16:55:00

Researchers seek to deny HIV its safe havens in the human body A drug already used to treat parasitic infections, and once looked at for cancer, also attacks the human immunodeficiency virus (HIV) in a new and powerful way, according to research published today online in the open access journal Retrovirology. Past research has established that HIV has "learned" to hide out in certain human cells where it is safe from the body's counterattack, cells that come to serve as viral reservoirs....


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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