Latest Mir-96 microRNA Stories

2011-01-21 15:54:57

New research from the University of Sheffield has revealed that the molecular mechanism underlying deafness is caused by a mutation of a specific microRNA called miR-96. The discovery could provide the basis for treating progressive hearing loss and deafness. The research team, led by Dr Walter Marcotti, Royal Society University Research Fellow from the University's Department of Biomedical Science, in collaboration with Professor Karen Steel at the Sanger Institute in Cambridge, discovered...

2010-04-21 13:48:26

The genes in humans and many other species have been surveyed but their operating principles remain rather unknown. Researchers do not know precisely how genes guide development of various human tissues, or what causes developmental disorders. MicroRNA molecules, are recently identified regulatory factors, whose on-going analysis, provide more insight into the matter. This week, a team from the Institute of Biotechnology of the University of Helsinki, Duke University, Uppsala University and...

2010-02-08 08:12:21

Mimicking hereditary deafness in a mouse brings doctors closer to a cure Deafness is the most common disorder of the senses. Tragically, it commonly strikes in early childhood, severely damaging an affected child's ability to learn speech and language. In many cases, children gradually lose their hearing to become profoundly deaf over a long period of months to years, but scientists know very little about how this progressive loss happens, making prospects for prevention and cure very slim....

2009-04-28 07:46:33

Scientists of Helmholtz Zentrum Mnchen have developed a new mouse model that can be associated with deafness. With this model they succeeded for the first time in showing that microRNA, a new class of genes, influences hearing loss. The respective microRNA seed region influences the production of sensory hair cells in the inner ear, both in the mouse and in humans. The findings have been published ahead of print in the current online issue of Nature Genetics. This study represents a major...

2009-04-15 07:53:55

Despite modern medicine, one in 1,000 American babies are born deaf. The numbers increase markedly with age, with more than 50% of seniors in the United States experiencing some form of hearing loss.But the era of the hearing aid, and shouting at aging in-laws, may soon be over.  A new, landmark study by a world-renowned geneticist and hearing loss expert at Tel Aviv University has uncovered one of the root causes of deafness.Prof. Karen Avraham of the Department of Human Molecular...

2009-04-14 12:22:07

Parallel studies in mice and humans by Spanish and British scientists have found a new kind of genes -- micro RNAs -- are linked to progressive hearing loss. The researchers said their findings provide important new genetic understanding of a condition that's common in humans yet remains poorly understood. The Spanish scientists from the Hospital Ramon Cajal in Madrid followed families who showed hearing loss. The second team, led by British researchers from the Wellcome Trust Sanger...

2009-04-13 07:48:42

Human and mouse share hearing deficit caused by mutation in microRNA In parallel studies in human and mouse, two groups of researchers have come to the same conclusion: that a new kind of gene is associated with progressive hearing loss. The new gene - called a microRNA - is a tiny fragment of RNA that affects the production of hundreds of other molecules within sensory hair cells of the inner ear. The research provides important new genetic understanding of a condition that is common in...

Word of the Day
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.