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Last updated on April 18, 2014 at 17:24 EDT

Latest mitochondria Stories

2014-04-04 23:33:51

By illuminating mitochondria, UVA researchers shed light on disease and human health. Charlottesville, VA (PRWEB) April 03, 2014 Under the microscope, they glow like streetlights, forming tidy rows that follow the striations of muscle tissue. They are mitochondria, the powerhouses of cells, and researchers at the University of Virginia School of Medicine have created a method to illuminate and understand them in living creatures like never before. Not only can the researchers make the...

2010-08-03 13:12:16

A team of scientists at the University of California, Davis, and the University of Auckland has discovered that neuroglobin may protect against Alzheimer's disease by preventing brain neurons from dying in response to natural stress A team of scientists at the University of California, Davis and the University of Auckland has discovered that neuroglobin may protect against Alzheimer's disease by preventing brain neurons from dying in response to natural stress. The team published the results...

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2010-05-10 12:15:56

Mutations that cause Parkinson's disease prevent cells from destroying defective mitochondria, according to a study published online May 10 in the Journal of Cell Biology. Defects in the ubiquitin ligase Parkin are linked to early-onset cases of this neurodegenerative disorder. The wild-type protein promotes the removal of impaired mitochondria by a specialized version of the autophagy pathway called mitophagy, delivering mitochondria to the lysosomes for degradation. Mitochondria are often...

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2009-10-13 10:27:09

International research teams has shown that parts of the genetic programs that determine programmed cell death in plants and animals are actually evolutionarily related and moreover function in a similar way Research has previously assumed that animals and plants developed different genetic programs for cell death. Now an international constellation of research teams, including one at the Swedish University of Agricultural Sciences, has shown that parts of the genetic programs that determine...

2009-03-03 08:35:00

Knowledge of mitochondrial processes could aid understanding of neurodegenerative diseaseMitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial growth and degradation are also part of the equation.The study will appear online March 2, 2009 (www.jcb.org) and in the March 9, 2009 print issue of The Journal of Cell Biology (JCB).Fission is...

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2008-11-24 13:15:00

A new study by Narendra et al. suggests that Parkin, the product of the Parkinson's disease-related gene Park2, prompts neuronal survival by clearing the cell of its damaged mitochondria. "[This is] an exciting new discovery that links the fields of mitochondrial quality control and the genetics of Parkinson's disease (PD)," writes Heidi McBride of the University of Ottawa Heart Institute. ""¦This work significantly increases our understanding of PD and provides a new framework for the...

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2008-05-29 09:10:00

WASHINGTON -- In an act of ultimate self-sacrifice, millions of human cells commit suicide every day, making your life better by their death. Some cells kill themselves so that developing embryos don't grow webs between their fingers and toes. In teenagers, unused brain cells are pruned away. Other cells kill themselves after damage by radiation or smoking. Now scientists are learning to control this biological demolition process and enlist it in the war on cancer. It's called...

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2005-06-09 17:08:39

New Haven, Conn. -- Researchers at Yale have identified a gene that regulates the major immune response in plants, programmed cell death (PCD), according to a recent report in the journal Cell. To protect themselves from viruses, plants create a zone of dead cells around an infection site that prevents the infection from spreading. Savithramma Dinesh-Kumar, associate professor of Molecular, Cellular and Developmental Biology at Yale and his colleagues discovered how the plants keep from...