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Latest Mitochondrial disease Stories

2014-07-02 12:20:39

The JAMA Network Journals Use of exome sequencing improved the ability to identify the underlying gene mutations in patients with biochemically defined defects affecting multiple mitochondrial respiratory chain complexes (enzymes that are involved in basic energy production), according to a study in the July 2 issue of JAMA. Defects of the mitochondrial respiratory chain have emerged as the most common cause of childhood and adult neurometabolic disease, with an estimated prevalence of...

2014-06-05 23:16:50

CEO and founder of Edison Pharmaceuticals has changed the lives of many children and families with mitochondrial disease BOSTON, MA (PRWEB) June 05, 2014 Guy Miller, MD, PhD, CEO and founder of Edison Pharmaceuticals has changed the lives of many children and families with mitochondrial disease. For his efforts, MitoAction recognized him with its “Making a Difference For Mito” award. Dr. Miller was chosen based on his extensive and ongoing contribution to the mitochondrial disease...

Three-Parent Conception Helps Reduce Risk Of Inherited Mitochondrial Disease
2014-06-03 12:53:49

Brett Smith for redOrbit.com - Your Universe Online To prevent deadly, inherited mitochondrial diseases – UK doctors have devised a unique scheme: create a fertilized embryo using eggs from two different women and sperm from one man. According to a new report from the country’s Human Fertilization and Embryology Authority (HFEA), the proposed procedure would be safe and possibly useful, setting the stage for a debate surrounding the ethics of engineering a three-parent child. The US...

2014-05-21 00:20:51

EPI-743 in phase 2B/3 development for Leigh syndrome MOUNTAIN VIEW, Calif., May 21, 2014 /PRNewswire/ -- Edison Pharmaceuticals today announced that the Japanese Ministry of Health, Labor and Welfare (MHLW) has granted Orphan Designation to EPI-743 for the treatment of Leigh syndrome. EPI-743 is currently in phase 2B development for the treatment of Leigh syndrome. A phase 2B randomized double-blind placebo-controlled trial in children with Leigh syndrome is fully enrolled in the...

2014-05-14 23:16:45

Awarded by the Smaller Business Association of New England, Inc. (SBANE) Billerica, MA (PRWEB) May 14, 2014 Seahorse Bioscience, the industry leader in metabolic analyzers and assay kits for measuring real-time cell metabolism, announces that it has been named the winner of the 2014 New England Innovation Award, from the Smaller Business Association of New England (SBANE). Seahorse was selected from 210 innovative organizations to compete in the final phase of this competition. Winners...

2014-04-14 10:56:31

Manipulating the metabolic process in cells may compensate for defects that can shorten cell life UAlberta researchers are taking a closer look at how two metabolic pathways interact to increase the lifespan of cells with mitochondrial defects. Magnus Friis (PhD ’10) is the lead author of the study, which was published online on April 10 and will be published in the April 24 issue of Cell Reports. Mitochondria produce energy for cells through oxidative metabolism, but the process...

2014-03-28 09:10:41

Mitochondria, long known as "cellular power plants" for their generation of the key energy source adenosine triphosphate (ATP), are essential for proper cellular functions. Mitochondrial defects are often observed in a variety of diseases, including cancer, Alzheimer's disease, and Parkinson's disease, and are the hallmarks of a number of genetic mitochondrial disorders whose manifestations range from muscle weakness to organ failure. Despite a fairly strong understanding of the pathology of...

2014-03-21 23:26:31

The conference offers physicians, nurses, and specialists an opportunity to understand more about identifying mitochondrial diseases, managing adults and children with mitochondrial disorders, and assisting patients with treatment options and coordinated care. Boston, MA (PRWEB) March 21, 2014 In an ongoing effort to improve mitochondrial disease patient care, MitoAction will host the 2014 Mitochondrial Disease Clinical Conference Boston on May 3, 2014 at Mandarin Oriental. This is...

2014-03-17 00:23:45

EPI-743 in two phase 2 development studies for Friedreich's ataxia MOUNTAIN VIEW, Calif., March 17, 2014 /PRNewswire/ -- Edison Pharmaceuticals today announced that the United States Food and Drug Administration granted Fast Track designation to EPI-743, the company's lead drug, for the treatment of Friedreich's ataxia. EPI-743 is being developed for pediatric and adult mitochondrial disease, including Friedreich's ataxia. EPI-743 has successfully completed phase 1 and multiple...

2014-03-10 00:21:49

First subject enrolled in pivotal clinical trial MOUNTAIN VIEW, Calif., March 10, 2014 /PRNewswire/ -- Edison Pharmaceuticals today announced the initiation of a phase 2B/3 study entitled, "A Phase 2B/3 Open-label Study of EPI-743 in Children with Leigh Syndrome" to be conducted in conjunction with Dainippon Sumitomo Pharma Co, Ltd. The trial is an open-label study lasting six months. To be eligible for the trial, children must have clinical and radiographic evidence of Leigh...


Word of the Day
glogg
  • Scandinavian punch made of claret and aquavit with spices and raisins and orange peel and sugar.
This word comes from the Swedish 'glogg,' which is an alteration of 'glodgat,' mulled (wine).
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