Latest Mitosis Stories

In the news release, BabelSecure announces litigation against Spindle Inc., issued today by BabelSecure LLC over PR Newswire, we are advised by the company that the headline should read "BabelSecure announces litigation against Spindle Mobile Inc, aka Spindle Inc." rather than "BabelSecure announces litigation against Spindle Inc." as originally issued inadvertently. The complete, corrected release follows: BabelSecure announces litigation against Spindle Mobile Inc, aka Spindle Inc....

TUCSON, Ariz., March 14, 2013 /PRNewswire/ -- BabelSecure LLC announced today that a lawsuit was filed on December 6, 2012, in the Superior Court of the State of Arizona (docket umber C201127533) by two principal shareholders, Mr. Mark Ogram and Mr. Wayne Rod, against Spindle Mobile Inc., the predecessor to Spindle Inc. (SPDL). Included in the lawsuit are the individual members of the Spindle Inc. Board of Directors. The lawsuit states that Spindle Mobile Inc. is also known as...

Researchers at the University of Geneva, Switzerland, demonstrate that the receptors that bind the toxin of this bacterium control how cell division is oriented Anthrax uses a receptor on the surface of cells to inject its lethal toxins. However, the physiological function of this receptor, named Anthrax Toxin Receptor 2a (Antxr2a), remained unknown until now. A team led by Marcos Gonzalez-Gaitan, a professor at the University of Geneva (UNIGE), Switzerland, in collaboration with Gisou van...

Biologists have identified a new molecular player in asymmetric cell division, a protein named She1 whose role wasn't known before - This is important for self-renewal of stem cells and ensures that daughter cells have different fates and functions Recently biologists at the University of Massachusetts Amherst led by Wei-lih Lee have identified a new molecular player in asymmetric cell division, a regulatory protein named She1 whose role in chromosome- and spindle positioning wasn't known...

The Nek9 protein is required for chromosomes to separate into two identical groups. Nek9 exerts its action between two molecules of interest for the pharmaceutical industry as anti-tumoral agents, and for which inhibitors are already in advanced stages of clinical trials. Nek9 could be added to the list of candidates. A study by the Institute for Research in Biomedicine (IRB Barcelona) and the Center for Genomic Regulation (acronym in Catalan CRG) highlights the protein Nek9 as a...

--Researchers at The Children's Hospital of Philadelphia Identify New Gene in Cornelia deLange Syndrome-- PHILADELPHIA, Aug. 13, 2012 /PRNewswire-USNewswire/ -- Genetics researchers have identified a key gene that, when mutated, causes the rare multisystem disorder Cornelia deLange syndrome (CdLS). By revealing how mutations in the HDAC8 gene disrupt the biology of proteins that control both gene expression and cell division, the research sheds light on this disease, which...

Stowers team reconciles puzzling findings relating to centromere structure Scientists at the Stowers Institute of Medical Research have developed an innovative method to count the number of fluorescent molecules in a cluster and then applied the novel approach to settle a debate rampant among cell biologists—namely, how DNA twists into a unique chromosomal structure called the centromere. Knowing this helps explain how cells navigate the hazards of division and avoid the disastrous...

Children's Hospital of Philadelphia researchers shed light on genetic disorders tied to cohesin protein malfunction Researchers studying rare genetic disorders have uncovered insights into those diseases in biological structures that regulate chromosomes when cells divide. Focusing on the cohesin complex, a group of proteins forming a bracelet that encircles chromosome pairs, scientists have discovered mutations that disrupt cohesin, causing a recently recognized class of diseases called...

The foundation of biological inheritance is DNA replication This is a coordinated process in which DNA is copied at hundreds of thousands of different sites across the genome at the same time. If the copying mechanism doesn't work properly, the result may be cells with missing or extra genetic material, a hallmark of the genomic instability seen in most birth defects and cancers. Scientists at the University of North Carolina School of Medicine have discovered a protein known as Cdt1....

They have identified new functions of cohesin SA1 that are relevant for cancer and CdLS Cohesin is a ring-shaped protein complex involved in the spatial organization of the genome and in mitotic chromosome structure. Vertebrate somatic cells have two versions of cohesin that contain either SA1 or SA2, but their functional specificity has been largely ignored. Researchers of the Spanish National Cancer Research Centre (CNIO) under the direction of Ana Losada have identified new functions of...