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Latest Mitosis Stories

2011-04-05 00:05:23

Discovery points to a potential co-contributor to cilia-related diseases Researchers at the University of Massachusetts Medical School have described a previously unknown role for the cilia protein IFT88 in mitosis, the process by which a dividing cell separates its chromosomes containing the cell's DNA into two identical sets of new daughter cells. Published in advance online by Nature Cell Biology, this newly discovered function for IFT88 suggests a possible alternative or contributory...

2011-01-13 14:25:06

In the case of DNA, the package can be as important as its contents, new work with fruit flies reveals. In 2003, the year a complete draft of the human genome was released, the U.S. National Human Genome Research Institute launched the ENCODE project (ENCyclopedia of DNA Elements), to develop an encyclopedia of the epigenome, that is, of all of the many factors that can change the expression of the genes without changing the genes. Four years later, the National Institutes of Health funded...

2010-12-01 22:49:16

University of Michigan researchers have discovered that a protein known to regulate cellular metabolism is also necessary for normal cell division in blood-forming stem cells. Loss of the protein results in an abnormal number of chromosomes and a high rate of cell death. The finding demonstrates that stem cells are metabolically different from other blood-forming cells, which can divide without the protein, Lkb1. This metabolic difference could someday be used to better control the behavior...

2010-11-25 22:08:47

Accurate gene distribution during cell division depends on stable set-up Scientists have discovered an amazingly simple way that cells stabilize their machinery for forcing apart chromosomes. Their findings are reported Nov. 25 in Nature. When a cell gets ready to split into new cells, this stable set-up permits its genetic material to be separated and distributed accurately. Otherwise, problem cells "“ like cancer cells"” arise. The human body contains more than a trillion cells,...

2010-11-17 17:08:28

Teams from UK and Germany publish research in Nature Cell Biology New research that provides potential for exciting new approaches to targeting diseases such as cancer has been announced by an international team of academics. They have also announced the potential for more targeted treatments following their identification of proteins that play a vital role in the life of a human cell. The research teams from Germany and the UK have published their work in the Advance Online Publication on...

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2010-11-16 13:38:19

Dr. Joseph Glavy at Stevens Institute of Technology studies the smallest and most basic elements of life. The Assistant Professor of Chemical Biology runs the Glavy Lab, where advanced student scientists study the nuclear pore complexes (NPCs) in cells, observing the minutest mechanisms of life as they unfold during mitosis. The Glavy Lab's formal purpose is to study the NPC at the molecular level in the pursuit of the unknown or unexpected in the well-studied but not always well-understood...

2010-11-09 06:00:00

ROCKVILLE, Md., Nov. 9, 2010 /PRNewswire-FirstCall/ -- EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer, today announced presentations for its Phase 2 oncology drug candidate, ENMD-2076. Data for the ENMD-2076 Phase 1 studies in multiple myeloma and leukemia will be presented by EntreMed investigators at the 2010 Annual Meeting of the American Society of Hematology (ASH) to be held December 4-7 at the Orange County...

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2010-10-15 08:16:31

Unless you are in a field of study related to cell biology, you most likely have never heard of Ndc80. Yet this protein complex is essential to mitosis, the process by which a living cell separates its chromosomes and distributes them equally between its two daughter cells. Now, through a combination of cryo-electron microscopy and three-dimensional image reconstruction, a team of researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC)...

2010-10-11 14:30:52

Researchers at the Carnegie Institution for Science, with colleagues at the Nara Institute of Science and Technology, observed for the first time a fundamental process of cellular organization in living plant cells: the birth of microtubules by studying recruitment and activity of individual protein complexes that create the cellular protein network known as the microtubule cytoskeleton"”the scaffolding that provides structure and ultimately form and shape to the cell. These fundamental...

2010-09-09 10:51:51

University of Pennsylvania biologists studying human reproduction have identified what is likely the major contributing factor to the maternal age-associated increase in aneuploidy, the term for an abnormal number of chromosomes during reproductive cell division. Using naturally aging mouse models, researchers showed that this basic fact of reproductive life is most likely caused by weakened chromosome cohesion.  Older oocytes, or egg cells, have dramatically reduced amounts of a...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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