Latest Mobile genetic elements Stories
A long-standing barrier to successful gene therapy in humans has been the lack of a non-toxic and effective tool or vector to carry the gene into the cell.
Tiny wound-up circular bits of DNA that carry a short "hairpin" of RNA could prove a solution to the quest for a non-toxic, long-lived gene therapy vector designed to silence cancer genes in tumor cells.
Researchers have developed a genetic tool in mice to speed the discovery of novel genes involved in cancer.
Building on a tool that they developed in yeast four years ago, researchers at the Johns Hopkins University School of Medicine scanned the human genome and discovered what they believe is the reason people have such a variety of physical traits and disease risks.
Under the microscope, the bacteria start dividing normally, two cells become four and then eight and so on.
Finding has new implications for understanding genetic diseases.
Using high-throughput sequencing to map the locations of a common type of jumping gene within a person's entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic diversity.
For two decades, the laboratory mouse has been the workhorse of biomedical studies and the only mammal whose genes scientists could effectively and reliably manipulate to study human diseases and conditions.
Genetic variation due to DNA mutation is a driving force of adaptation and evolution, as well as a contributing factor to disease.
Jumping Elements, Some of Which Cause Genetic Diseases, Become Incorporated in the Genome at Different Stages of Human Development.
- One of a pair of round metal cymbals attached to the fingers and struck together for rhythm and percussion in belly dancing.