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Last updated on April 19, 2014 at 1:20 EDT

Latest Model for End-Stage Liver Disease Stories

2013-11-02 08:21:39

Presented: November 3, 2013, Walter E. Washington Convention Center, Washington, DC WASHINGTON, Nov. 2, 2013 /PRNewswire/ -- Up to now, liver transplantation for patients with neuroendocrine tumors of gastroentero-pancreatic (GEP-NET) has been controversial because accepted selection criteria are lacking, benefit in survival is unproven, and allocation of donated liver grafts for these patients still does not rely on reproducible results. Nontransplant treatment options for these...

2013-07-12 12:44:18

'It's not fair that where you live so vastly affects your ability to get a transplant' Using the same type of mathematical formulas used to draw political redistricting maps, Johns Hopkins researchers say they have developed a model that would allow for the more equitable allocation of livers from deceased donors for transplantation. Currently, in the United States, where you live dictates the availability of a liver transplant. Studies show that geography can mean the difference...

2012-07-11 06:00:43

Researchers from Spain established that liver stiffness, measured by transient elastography (TE), is an independent predictor of liver failure, hepatocellular carcinoma (HCC), and mortality in cirrhotic patients coinfected with the human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS), and hepatitis C virus (HCV). Findings available in the July issue of Hepatology, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases,...

2012-03-22 22:39:46

Experts call for evaluation of current criteria for allocating organs for transplantation New research shows increasing disparity in mortality among candidates with and without hepatocellular carcinoma (HCC) who are on the waiting list for liver transplantation. The study available in the April issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, found that liver cancer patients are less likely to...

2011-09-27 14:53:13

Patients with liver cancer and low MELD scores may not find similar benefit New research shows liver transplantation candidates without hepatocellular carcinoma (HCC) derive a greater survival benefit from a living donor liver transplant (LDLT) than waiting for a deceased donor liver transplant (DDLT). The study now available in the October issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, reports that...

2011-09-09 13:34:02

Reducing mortality of patients on transplantation waitlist is top priority Transplantation specialists have proposed changes to the allocation and distribution of organs used for liver transplants. The recommended policy modifications take into account the scarcity of available organs, ensuring rapid allocation and delivery of the organ to those most in need in order to reduce mortality for waitlisted patients. Details of the proposed model are available in the September issue of Liver...

2010-08-19 15:05:05

Study links locale to diminished access to organs Researchers at the University of Michigan and Arbor Research Collaborative for Health, both in Ann Arbor, have identified geographic variation as a key factor accounting for disparities in access to liver transplantation among racial and ethnic groups. Full details appear in the September issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD). Organ...

2010-04-16 14:28:47

Results show limited survival advantage, only in specific patient types Results from two studies presented today at the International Liver CongressTM 2010 have shown that treatment with extracorporeal devices may not confer a survival advantage for severe liver failure patients, despite positive dialysis effects. However, results among a small sub-group of patients show promise. Extracorporeal liver support therapy is in its infancy but is valued as a detoxification treatment option for...

2009-11-02 05:00:00

ALEXANDRIA, Va. and BOSTON, Nov. 2 /PRNewswire/ -- A methacetin breath test (MBT) that can be performed quickly and noninvasively has been proven to accurately predict survival in patients with viral hepatitis and may be used as an adjunctive tool to MELD. "The breath test has to be validated on a large cohort of patients," said Gadi Lalazar, MD, principal investigator on this study "but if it is validated, this non invasive liver function test will be able to identify liver impairment at...

2009-08-28 09:43:27

According to the Centers for Disease Control and Prevention (CDC) 1.5 to 2 million Americans are infected with the hepatitis B virus (HBV). Prior studies have shown there to be significant racial differences in access to and outcomes of liver transplantation. Recently, doctors from across the U.S. conducted a multicenter retrospective-prospective study of the waitlist status and outcomes of liver transplant patients with HBV infection. This study led by Natalie Bzowej from California Pacific...