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Latest Molecular mimicry Stories

Surprising Similarities In The Way Immune System Defenders Bind To Disease-causing Invaders
2014-05-27 03:50:47

By Glenn Roberts Jr., Stanford University A study led by researchers at Stanford's School of Medicine reveals how T cells, the immune system's foot soldiers, respond to an enormous number of potential health threats. X-ray studies at the Department of Energy's SLAC National Accelerator Laboratory, combined with Stanford biological studies and computational analysis, revealed remarkable similarities in the structure of binding sites, which allow a given T cell to recognize many...

2012-04-10 13:53:32

New method for direct identification of antigens The immune system is a vital part of our defenses against pathogens, but it can also attack host tissues, resulting in autoimmune disease. The antigens that induce destructive immune reactions can now be identified directly — without any prior knowledge of their possible structure. Molecules that activate immune responses, generically termed antigens, are recognized by circulating immune cells. In the case of autoimmune reactions,...

2011-12-23 10:17:41

A research team led by Glenn Rall at the Fox Chase Cancer Center in Philadelphia, PA developed a novel mouse model to show that a fatal central nervous system (CNS) disease can be caused by a pathogen that does not replicate in the CNS. The results of this new study are published December 22nd in the Open Access journal PLoS Pathogens. The authors found that the immune response induced in response to a peripheral viral infection can be "mis-recruited" to the brain, where these activated...

2011-01-24 18:16:23

Antibodies are watchdogs of human health, continuously prowling the body and registering minute changes associated with infection or disease with astonishing acuity. They also serve as biochemical memory banks, faithfully recording information about pathogens they encounter and efficiently storing this data for later use. Stephen Albert Johnston, Neal Woodbury and their colleagues at the Biodesign Institute at Arizona State University have been exploring mechanisms of antibody activity,...

2007-01-10 03:00:11

By Thirkill, C E ABSTRACT Cancers induce a loss of homeostasis through the uncontrolled production and release of a variety of biologically active cellular products, natural compounds produced in unnatural quantities within abnormal anatomical locations. Often, there is an immune response to which the cancerous growth may succumb, or have the characteristics required to survive. If, during its proliferation, the cancer should coincidentally express a potent autoantigen then the organ in...


Word of the Day
ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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