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Latest Molecular neuroscience Stories

2014-06-11 23:11:43

The article published in AIMS Neuroscience explains how cortical microcircuitry is conducive to column formation. The column is the information bit proposed in the Dimensional Systems Model as the basis for learning and memory. Greenville, SC (PRWEB) June 11, 2014 Clinical neuropsychologist Robert A. Moss, Ph.D., FACPN, FAACP, and cognitive psychologist Jarrod Moss, Ph.D., are the authors of an article on cortical columns in the explanation of gamma-band synchrony and NMDA receptors in...

2014-05-26 13:27:58

Canadian Association for Neuroscience Mechanism uncovered could also help preserve neuron function in Alzheimer's disease, traumatic brain injury and other neurodegenerative conditions Research presented by Dr. Lynn Raymond, from the University of British Columbia, shows that blocking a specific class of glutamate receptors, called extrasynaptic NMDA receptors, can improve motor learning and coordination, and prevent cell death in animal models of Huntington disease. As Huntington...

2014-05-21 11:48:44

Saint Louis University A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease. The molecule also reduced inflammation in the part of the brain responsible for learning and memory. The paper, authored by a team of scientists led by Susan Farr, Ph.D., research professor of geriatrics at Saint Louis University,...

2014-04-14 14:20:45

Alzheimer's disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government's annual revenues. Unfortunately, it has proven very difficult to develop drugs capable of ameliorating the disease. After a tremendous burst of progress in the 1990s, the pace of discoveries has slowed. Dr. Saido believes that...

Gordon Supercomputer Helps Guide New Drug Designs
2014-02-19 12:45:35

University of California, San Diego Single amyloid-beta monomers can pair up to form a variety of dimers that can aggregate into larger peptide rings that reside on cell membranes such as those pictured. This process has been implicated in the development of Alzheimer’s disease. This visualization shows the possible rings which have the most favorable energies of interactions with the membrane. The residues are colored white to represent apolar or hydrophobic areas, green for the polar...

Unraveling Mysteries Of Amyloid Beta Peptides To Detect And Treat Alzheimer's Disease
2014-02-18 07:41:38

American Institute of Physics Alzheimer's disease has long been marked by progress -- but not the kind of progress the medical community seeks. It is the most common form of dementia among older Americans, and its risk increases with increasing age; for those living with the disease, its ravages get worse over time; and as we move into the 21st century, it will place a greater and greater burden on society. The number of Americans living with Alzheimer's has doubled since 1980 and is...

2013-12-05 23:40:35

The N-methyl-D-aspartic acid (NMDA) receptor dysfunction in the brain of aged animals has been shown. In older rodents, N-methyl-D-aspartate receptor 2B subunit gene expression declines significantly associated with memory impairment. To further reveal this process, Dr. Chunxia Li and colleagues from East China Normal University, China analyzed gene expression profiles in the neocortex of aged Tg mice. Pathway and signal-net analyses identified multiple pathways altered in the transgenic...

Brain's Long-Term Reward System Relies On Dopamine
2013-08-05 10:15:52

Brett Smith for redOrbit.com - Your Universe Online From driving across country to graduating from college, long-term goals are often difficult to stay focused on when an immediate reward isn't within sight. A team of researchers from the University of Washington in Seattle and MIT has recently discovered new details on how the brain is able to stay focused until these long-term goals are achieved, according to a report in the journal Nature. The joint team's research builds on...

2013-07-26 14:12:08

Study first to use 'structural' approach in hunt for amyloid-inhibiting agents UCLA chemists and molecular biologists have for the first time used a "structure-based" approach to drug design to identify compounds with the potential to delay or treat Alzheimer's disease, and possibly Parkinson's, Lou Gehrig's disease and other degenerative disorders. All of these diseases are marked by harmful, elongated, rope-like structures known as amyloid fibrils, linked protein molecules that form...

Researchers Quantify Brain Protein Changes In Alzheimer Patients
2013-06-13 08:30:44

April Flowers for redOrbit.com - Your Universe Online A significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer's disease and healthy family members who do not have it has been measured by researchers at Washington University School of Medicine in St. Louis. Researchers have long known that a protein fragment called amyloid beta builds up into plaques in Alzheimer´s patient´s brains. The theory is that these plaques...


Word of the Day
glogg
  • Scandinavian punch made of claret and aquavit with spices and raisins and orange peel and sugar.
This word comes from the Swedish 'glogg,' which is an alteration of 'glodgat,' mulled (wine).
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