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Latest Monoamine oxidase inhibitor Stories

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2011-08-04 06:45:00

Antidepressant use and the risk of adverse outcomes in older people: population-based cohort study New generation antidepressants, known as selective serotonin reuptake inhibitors (SSRIs) are associated with an increased risk of several severe adverse outcomes in older people compared with older tricyclic antidepressants (TCAs), finds a study published in the British Medical Journal on August 3. The authors say the risks and benefits of different antidepressants should be carefully evaluated...

2010-10-08 10:46:00

ABBOTT PARK, Ill., Oct. 8 /PRNewswire/ -- Abbott (NYSE: ABT) will voluntarily withdraw Meridia® (sibutramine) from the U.S. market at the request of the U.S. Food and Drug Administration (FDA). The FDA's request is based primarily on the results of the SCOUT (Sibutramine Cardiovascular OUTcome Trial) study, an approximately 10,000 patient, 6-year study requested by European regulatory authorities as a post-marketing commitment to evaluate cardiovascular safety in...

2010-09-15 16:03:00

ABBOTT PARK, Ill., Sept. 15 /PRNewswire-FirstCall/ -- The U.S. Food and Drug Administration (FDA) today held an Endocrinologic and Metabolic Drugs Advisory Committee to review the results of SCOUT (Sibutramine Cardiovascular OUTcome Trial) and the weight loss medication sibutramine (sold as Meridia® in the United States). In response to the Advisory Committee's mixed vote, Abbott (NYSE: ABT) issued the following statement: "Today's vote highlights the complexity of this...

2009-05-22 08:00:00

PHILADELPHIA, May 22 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, Nasdaq: SHPGY), the global specialty biopharmaceutical company, announced results of a study showing that coadministration of the ADHD medication VYVANSE(R) (lisdexamfetamine dimesylate) CII with the proton pump inhibitor (PPI) Prilosec OTC(R) 40 mg (20 mg X 2), did not alter the median time it took for maximum plasma concentration of d-amphetamine to be reached in the subjects evaluated. In the same study, coadministration...

2009-04-20 07:00:00

NEW YORK and SAN DIEGO, April 20, 2009 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX) and Cypress Bioscience, Inc. (Nasdaq: CYPB) announced today that Savella(TM) (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor approved for the management of fibromyalgia, will be shipped to wholesalers on April 24th and will be available at pharmacies beginning on April 28th. After Savella was approved by the U.S. Food and Drug Administration (FDA) on...

2009-01-14 18:24:00

New treatment option for the estimated 6 million Americans living with this chronic, debilitating condition NEW YORK and SAN DIEGO, Jan. 14, 2009 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX) and Cypress Bioscience, Inc. (Nasdaq: CYPB) today announced that Savella(TM) (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor, was approved by the U.S. Food and Drug Administration (FDA) for the management of fibromyalgia. Fibromyalgia is a chronic...

2006-07-19 13:24:11

WASHINGTON (Reuters) - The use of some migraine drugs with certain antidepressants can cause a fatal condition in which patients experience hallucinations, overactive reflexes and rapid heart beat, the U.S. Food and Drug Administration warned on Wednesday. The antidepressants of concern include selective serotonin reuptake inhibitors and selective serotonin/norepinephrine reuptake inhibitors, the FDA said. Patients should talk to their doctors before discontinuing antidepressant or...

2005-07-28 14:45:12

BOSTON - Researchers from Harvard Medical School have found a molecule that is unexpectedly involved in dopamine signaling, and in a manner that supports the potential of dopamine as an alternative target for treating depression. The results provide evidence that there is a molecular link between impaired dopamine signaling and depression, which affects 16 percent of the adult population in the United States. The research appears in the July 29 issue of Cell. Li-Huei Tsai, Harvard Medical...


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