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Latest Monoamine oxidase Stories

2010-01-07 14:08:49

Monoamine oxidase-A inhibitor drug blocks buildup of toxic free radicals in animal hearts A team of Johns Hopkins and other researchers have found in animal experiments that an antidepressant developed over 40 years ago can blunt and even reverse the muscle enlargement and weakened pumping function associated with heart failure. In a report to be published in the Jan. 8 edition of the journal Circulation Research, the international team of U.S. and Italian heart experts describes in a dozen...

2009-12-08 19:40:06

A key brain protein called monoamine oxidase A (MAO-A) - is highly elevated during clinical depression yet is unaffected by treatment with commonly used antidepressants, according to an important study published today in the Archives of General Psychiatry. The study has important implications for our understanding of why antidepressants don't always work. Researchers at the Centre for Addiction and Mental Health (CAMH) used an advanced brain imaging method to measure levels of the brain...

2009-12-07 06:30:00

RESEARCH TRIANGLE PARK, N.C., Dec. 7 /PRNewswire/ -- CeNeRx BioPharma, Inc., a clinical stage company developing innovative treatments for diseases of the central nervous system, today announced that a newly published PET imaging study in human subjects confirms that CeNeRx's novel compound TriRima(TM) reversibly inhibits MAO-A (monoamine oxidase A), an enzyme in the brain that plays a key role in the regulation of mood. TriRima is a member of a new class of selective and reversible...

2009-09-29 00:51:56

A Finnish researcher says several factors, including abuse during childhood, may help predict the risk of violent behavior in men. Study author Dr. Roope Tikkanen, who published his doctoral dissertation on the findings, found severe personality disorders and childhood adversities -- especially childhood maltreatment -- increased the risk of recidivism and mortality in the 242 offenders in the study significantly more than in the 1,210 controls matched by age and place of birth. The...

2009-09-25 09:22:03

In the future, diagnosing severe personality disorders, evaluating the childhood environment, assessing alcohol consumption and the analysis of the MAOA genotype may provide more accurate means for assessing risk among violent offenders, according to the Finnish research carried out jointly at the University of Helsinki and the Helsinki University Central Hospital Psychiatry Centre. "The many negative effects of violence could be alleviated by improving the accuracy of predicting violent...

2009-09-13 08:21:59

Press conference at the 22nd Congress of the European College of Neuropsychopharmacology, Sept. 13, 2009, Istanbul, Turkey Antisocial and aggressive behaviors represent a widespread and expensive social problem. Recent research has convincingly shown that there is a strong interaction between genetic inheritance and environment for development of personality and behavior. It appears to be common knowledge that childhood maltreatment often causes psychiatric problems (e.g. depression or...

2009-07-21 19:26:38

A common variation of the gene involved in regulating serotonin and norepinephrine in the brain may be linked to problem behaviors in adults with developmental and intellectual disabilities, new research indicates.The findings were published in the July 2009 issue of the American Journal on Intellectual and Developmental Disabilities and are available online at http://tinyurl.com/mw8baj."Problem behaviors in these populations account for billions of dollars in intervention costs each year,...

2009-07-21 14:18:28

Placebos are a sham "” usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.And yet, for some people, the placebo works nearly as well as the medication. How well placebos work varies widely among individuals. Why that is so, and why they work at all, remains a mystery, thought to be based on some combination of biological and psychological...

2009-06-07 23:49:46

Boys who carry a variation of the gene Monoamine oxidase A, are more likely to join gangs and be among the most violent members, U.S. researchers said. Criminologist Kevin M. Beaver at Florida State University said the findings apply only to males -- not girls with the same variant of the so-called warrior gene. While gangs typically have been regarded as a sociological phenomenon, our investigation shows that variants of a specific MAOA gene, known as a 'low-activity 3-repeat allele,' play a...

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2009-06-05 11:20:00

Boys who carry a particular variation of the gene Monoamine oxidase A (MAOA), sometimes called the "warrior gene," are more likely not only to join gangs but also to be among the most violent members and to use weapons, according to a new study from The Florida State University that is the first to confirm an MAOA link specifically to gangs and guns. Findings apply only to males. Girls with the same variant of the MAOA gene seem resistant to its potentially violent effects on gang membership...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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