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Latest Monocyte Stories

2012-06-22 10:40:36

A study spearheaded by a Stanford University School of Medicine scientist has tracked the trajectories of key immune cells in response to short-term stress and traced, in great detail, how hormones triggered by such stress enhance immune readiness. The study, conducted in rats, adds weight to evidence that immune responsiveness is heightened, rather than suppressed as many believe, by the so-called "fight-or-flight" response. The study's findings provide a thorough overview of how a triad...

2012-03-26 11:05:03

Finding may help develop new treatments for infectious diseases, cancer UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections. Published March 25 online in Nature Medicine, the team specifically studied how dendritic cells, immune cells located at the site of infection, become more specialized to fight the leprosy pathogen known as Mycobacterium leprae. Dendritic cells, like scouts in the...

2012-02-10 10:31:58

Inflammatory breast cancer (IBC) is the most lethal form of breast cancer. It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed Central's open access journal Cell Communication and Signaling demonstrates how IBC cells use IL-8, secreted as part of the anti-inflammatory response by a specific set of white blood cells (monocytes), to increase fibronectin expression. Fibronectin is a cell-adhesion...

2012-02-02 22:41:13

Scientists at the University Medical Center in Mainz prove multiple DNA repair defect in monocytes Scientists working with Professor Bernd Kaina of the Institute of Toxicology at the Medical Center of Johannes Gutenberg University Mainz have demonstrated for the first time that certain cells circulating in human blood — so-called monocytes — are extremely sensitive to reactive oxygen species (ROS). They were also able to clarify the reason for this: ROS are aggressive forms of...

2012-01-31 09:45:38

A study of the cells that respond to crises in the blood system has yielded a few surprises, redrawing the ℠map´ of how blood cells are made in the body. The finding, by researchers from the Walter and Eliza Hall Institute, could have wide-ranging implications for understanding blood diseases such as myeloproliferative disorders (that cause excess production of blood cells) as well as used to develop new ways of controlling how blood and clotting cells are produced. The...

2011-12-13 12:17:46

Researchers at the University of Toronto have found an explanation for how the intestinal tract influences a key component of the immune system to prevent infection, offering a potential clue to the cause of autoimmune disorders like rheumatoid arthritis and multiple sclerosis. "The findings shed light on the complex balance between beneficial and harmful bacteria in the gut," said Prof. Jennifer Gommerman, an Associate Professor in the Department of Immunology at U of T, whose findings...

2011-11-10 18:32:51

Atherosclerosis, commonly referred to as "hardening of the arteries," is a major risk factor for heart attack and stroke. The cause of atherosclerosis is not well understood but, for some time, chronic inflammatory immune responses have been implicated in driving disease pathology. Now, a new study, published online on November 10th by Cell Press from the journal Immunity, identifies a type of immune cell that is not associated with promoting disease, but with protection against...

2011-10-11 12:13:17

An estimated 1.3 million people in the United States suffer from rheumatoid arthritis. The causes behind this chronic disease – which can exhibit itself as pain, swelling, stiffness, deformation, and loss of function in the joints – have eluded scientists for centuries. A new study by UNC researchers offers tantalizing glimmers about the roles of a gene called CCR2, an immune system cell called Th17 cell, and a missing monocyte. The study contributes to a better understanding...

2011-10-10 09:12:58

Interfering with cell recruitment reduces damaging inflammation in animals´ models of several disorders Massachusetts General Hospital (MGH) researchers — along with collaborators from Massachusetts Institute of Technology (MIT) and Alnylam Pharmaceuticals — have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication in Nature Biotechnology, the investigators...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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