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Latest Morphogenesis Stories

2014-05-23 11:10:34

UCSB UCSB study shows that key protein in epithelial cells plays important roles in how cells sense direction What do sled dogs and cell clusters have in common? According to research by UC Santa Barbara’s Denise Montell, they both travel in groups and need a leader to make sure they all follow in the same direction. Montell, Duggan Professor of Molecular Cellular and Developmental Biology, and colleagues worked on three independent projects involving E-cadherin, a protein found in...

Researchers Help Develop A Dynamic Model Of Tissue Failure
2013-12-12 17:45:57

University of Pennsylvania The idea of growing replacement tissue to repair an organ, or to swap it out for an entirely new one, is rapidly transitioning from science fiction to fact. Tissue engineering techniques are improving in their ability to generate three-dimensional masses of cells and provide them with vascular systems for keeping them alive, but a more mathematically rigorous approach for designing these tissues is still needed. Researchers at the University of Pennsylvania,...

Measuring Life's Tugs And Nudges
2013-12-09 19:12:18

Wyss Institute for Biologically Inspired Engineering at Harvard Tiny oil droplets help measure mechanical forces produced by living cells that shape tissues and organs; new method could improve diagnosis of cancer, hypertension, and many other diseases As embryonic tissue develops, cells push and pull on each other, and they must do so correctly for the tissue to develop properly. Now scientists at Harvard University have devised the first method to measure these forces in...

2013-10-15 12:20:24

Villi are small epithelial protrusions that serve to increase the surface area of the gut for efficient nutrient absorption. The mechanism of their formation during development was recently revealed by a study published in Science. The investigations, carried out by two research groups at Harvard University, were complemented by computational modelling carried out at the University of Jyväskylä and funded by the Academy of Finland. Villification (villus formation) has previously been...

2012-01-26 13:12:33

In a study that holds major implications for breast cancer research as well as basic cell biology, scientists with the U.S. Department of Energy (DOE)´s Lawrence Berkeley National Laboratory (Berkeley Lab) have discovered a rotational motion that plays a critical role in the ability of breast cells to form the spherical structures in the mammary gland known as acini. This rotation, which the researchers call “CAMo,” for coherent angular motion, is necessary for the cells to...

2011-12-15 13:14:16

• This transformation, which is common in embryonic development, is very similar to the process undergone by metastatic tumor cells. • The gene GATA 6 is sufficient and necessary for this change to happen. This gene is associated with many tumors of endodermal origin, such as those of the liver, pancreas and colon. Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have identified the gene GATA 6 as responsible for epithelial cells -which group together...

2011-06-16 21:31:40

Stem cell technologies have been proposed for cell-based diagnostics and regenerative medicine therapies. However, being able to make stem cells efficiently develop into a desired cell type -- such as muscle, skin, blood vessels, bone or neurons -- limits the clinical potential of these technologies. New research presented on June 16, 2011 at the annual meeting of the International Society for Stem Cell Research (ISSCR) shows that systematically controlling the local and global environments...

2010-03-29 09:25:53

One of the most intriguing questions in cancer research is what causes metastatic tumor migration, why some tumor cells manage to migrate to other parts of the body but others cells don't. International investigation conducted by Enrique Martín Blanco, CSIC researcher at the Institute of Biology of Barcelona, located in the Barcelona Science Park, reveals that cells make use of a natural mechanism for this. It happens to be a family of proteins that trigger cell migration in...

2008-08-22 03:00:15

By Ramis-Conde, Ignacio Drasdo, Dirk; Anderson, Alexander R A; Chaplain, Mark A J ABSTRACT In this article, we show, using a mathematical multiscale model, how cell adhesion may be regulated by interactions between E-cadherin and beta-catenin and how the control of cell adhesion may be related to cell migration, to the epithelial- mesenchymal transition and to invasion in populations of eukaryotic cells. E-cadherin mediates cell-cell adhesion and plays a critical role in the formation and...

2007-11-13 06:00:23

By Halldorsson, Skarphedinn Asgrimsson, Valthor; Axelsson, Ivar; Gudmundsson, Gudmundur Hrafn; Steinarsdottir, Margret; Baldursson, Olafur; Gudjonsson, Thorarinn Abstract Due to the cellular complexity of the airway epithelium, it is important to carefully define bronchial cell lines that capture the phenotypic traits of a particular cell type. We describe the characterization of a human bronchial epithelial cell line, VA10. It was established by transfection of primary bronchial epithelial...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.