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Last updated on April 19, 2014 at 18:42 EDT
Researchers Look For Cause Of Eye Mobility Disorder

Researchers Look For Cause Of Eye Mobility Disorder

By Steve Kehoe, The University of Iowa Normal development stalls in the nerves Imagine you cannot move your eyes up, and you cannot lift your upper eyelid. You walk through life with your head tilted upward so that your eyes look straight...

Latest Motor neuron Stories

2014-04-07 10:57:39

A new way to artificially control muscles using light, with the potential to restore function to muscles paralyzed by conditions such as motor neuron disease and spinal cord injury, has been developed by scientists at UCL and King’s College London. The technique involves transplanting specially-designed motor neurons created from stem cells into injured nerve branches. These motor neurons are designed to react to pulses of blue light, allowing scientists to fine-tune muscle control by...

2014-04-04 12:27:33

By studying nerve cells that originated in patients with a severe neurological disease, a University of Wisconsin-Madison researcher has pinpointed an error in protein formation that could be the root of amyotrophic lateral sclerosis. Also called Lou Gehrig's disease, ALS causes paralysis and death. According to the ALS Association, as many as 30,000 Americans are living with ALS. After a genetic mutation was discovered in a small group of ALS patients, scientists transferred that gene...

2014-03-04 14:06:51

New Keck School of Medicine of USC research finds vascular damage in mice with ALS contributes to early development of the neurodegenerative disease, while repairing damage delays disease progression Keck School of Medicine of USC neuroscientists have unlocked a piece of the puzzle in the fight against Lou Gehrig's disease, a debilitating neurological disorder that robs people of their motor skills. Their findings appear in the March 3, 2014, online edition of the Proceedings of the...

2014-02-07 12:51:08

Study in human cells may improve ability to identify useful drug targets In most cases of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, a toxin released by cells that normally nurture neurons in the brain and spinal cord can trigger loss of the nerve cells affected in the disease, Columbia researchers reported today in the online edition of the journal Neuron. The toxin is produced by star-shaped cells called astrocytes and kills nearby motor neurons. In ALS, the death...

2014-01-10 10:59:12

Zebrafish study connects data between fish and mammalian locomotion We might have more in common with a lamprey than we think, according to a new Northwestern University study on locomotion. At its core, the study of transparent zebrafish addresses a fundamental evolution issue: How did we get here? Neuroscientists Martha W. Bagnall and David L. McLean have found that the spinal cord circuits that produce body bending in swimming fish are more complicated than previously thought....

2013-10-11 12:47:54

Researchers at the University of Toronto discover how the body's muscles accidentally fall asleep while awake Normally muscles contract in order to support the body, but in a rare condition known as cataplexy the body's muscles "fall asleep" and become involuntarily paralyzed. Cataplexy is incapacitating because it leaves the affected individual awake, but either fully or partially paralyzed. It is one of the bizarre symptoms of the sleep disorder called narcolepsy. "Cataplexy is...

2013-09-04 08:28:45

When the tiny roundworm C. elegans reaches middle age—at about 2 weeks old—it can't quite move like it did in the bloom of youth. But rather than imposing an exercise regimen to rebuild the worm's body-wall muscles, researchers can bring the wriggle back by stimulating the animal's neurons. And, they say, pharmaceuticals might have a similar effect in mammals. Scientists at the University of Michigan's Life Sciences Institute and Medical School have found that the loss of motor ability...

2013-05-01 13:08:31

Brain's elusive motor neurons are dressed in fluorescence so scientists can find them and study why they die A small group of elusive neurons in the brain's cortex play a big role in ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims. But the neurons have always been difficult to study because there are so few of them and they look so similar to other neurons in the cortex. In a new preclinical study, a Northwestern Medicine®...

Neuron Transformation In The Brain Opens A New Avenue In Neurobiology
2013-01-21 04:44:13

redOrbit Staff & Wire Reports - Your Universe Online A pair of Harvard University stem cell biologists have reportedly demonstrated a technique with which they can transform one type of already differentiated neuron into another. The discovery, reported by the Cambridge, Massachusetts-based Ivy League school in a statement released Sunday, demonstrates it is possible that the human brain “is not as immutable as we always thought, because at least during an early window of time...

2013-01-08 10:05:13

Insect research yields insights for muscle control and nerve disorders in mammals, including humans Working with fruit flies, Johns Hopkins scientists have decoded the activity of protein signals that let certain nerve cells know when and where to branch so that they reach and connect to their correct muscle targets. The proteins´ mammalian counterparts are known to have signaling roles in immunity, nervous system and heart development, and tumor progression, suggesting broad...