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Last updated on April 24, 2014 at 1:21 EDT

Latest Motor protein Stories

2014-03-27 13:10:03

Gene encodes protein that regulates formation and maintenance of muscle tissue Skeletal muscle cells with unevenly spaced nuclei, or nuclei in the wrong location, are telltale signs of such inherited muscle diseases as Emery-Dreifuss muscular dystrophy, which occurs in one out of every 100,000 births, and centronuclear myopathy, which affects one out of every 50,000 infants. What goes wrong during myogenesis, the formation and maintenance of muscle tissue, to produce these inherited...

2012-02-13 13:16:03

To solve a mystery, sometimes a great detective need only study the clues in front of him. Like Agatha Christie's Hercule Poirot and Arthur Conan Doyle's Sherlock Holmes, Tomomi Kiyomitsu used his keen powers of observation to solve a puzzle that had mystified researchers for years: in a cell undergoing mitotic cell division, what internal signals cause its chromosomes to align on a center axis? "People have been looking at these proteins and players in mitosis for decades, and no one ever...

2011-04-19 15:02:12

New insight into the physiology of cardiac muscle may lead to the development of therapeutic strategies that exploit an inherent protective state of the heart. The research, published by Cell Press online on April 19th in the Biophysical Journal, discovers a state of cardiac muscle that exhibits a low metabolic rate and may help to regulate energy use and promote efficiency in this hard-working and vital organ. Muscle cells are highly specialized cells that are able to physically contract and...

2009-11-30 16:10:14

EMBL scientists are the first to visualize the mechanism responsible for oskar mRNA transport In the fruit fly Drosophila, oskar mRNA, which is involved in defining the animal's body axes, is produced in the nuclei of nurse cells neighboring the oocyte, and must be transported to the oocyte and along its entire length before being translated into protein. Scientists in the group of Anne Ephrussi at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have visualized the...

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2009-11-24 12:23:36

The atomic-level action of a remarkable class of ring-shaped protein motors has been uncovered by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) using a state-of-the-art protein crystallography beamline at the Advanced Light Source (ALS). These protein motors play pivotal roles in gene expression and replication, and are vital to the survival of all biological cells, as well as infectious agents, such as the human papillomavirus, which has been linked to cervical...

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2009-08-17 16:25:00

"A biologist, a physicist, and a nanotechnologist walk into a ..." sounds like the start of a joke. Instead, it was the start of a collaboration that has helped to decipher a critical, but so far largely unstudied, phase of how cells divide. Errors in cell division can cause mutations that lead to cancer, and this study could shed light on the role of chromosome abnormalities in uncontrolled cell replication.The biologist in question is University of Pennsylvania School of Medicine Associate...

2008-06-27 06:02:23

By Dinh, Anh-Tuan Pangarkar, Chinmay; Mitragotri, Samir Unlike macroscopic problems in mass, energy and momentum transfer, which are described by continuum equations, the movements and interactions of the nanoscale entities within a cell constitute a transport phenomenon known as discrete nanoscale transport (DNT). Imagine yourself on an alien spaceship, watching the daily goings- on of a large city through a telescope. You would see (among other things) complex transportation systems...