Latest Mu Opioid receptor Stories

2014-09-29 08:30:53

DARIEN, Conn., Sept. 29, 2014 /PRNewswire/ -- Cytogel Pharma announces the presentation at the 8th Annual Pain and Migraine Therapeutics Summit of a mechanism of action study conducted in the laboratory of Gavril Pasternak, MD, PhD at Memorial Sloan Kettering Cancer Center in New York City. Cyt-1010 is a chemically stabilized and peptidase resistant analog of endomorphin-1, is highly mu-selective, showing very poor affinity for delta and kappa opioid receptors. Despite its mu...

2012-07-06 10:55:17

Frequently recommended in weight-loss diets, dietary proteins have proven effectiveness thanks to their appetite-suppressing effects. A team led by Gilles Mithieux, Director of Inserm's Unit 855 "Nutrition and the Brain" in Lyon, has managed to explain the biological mechanisms behind these properties. The researchers describe in detail the chain reactions triggered by digesting proteins, sending a 'satiety' message to the brain long after a meal. Their results will make it possible envisage...

Researchers Look At Why Alcohol Is Addicting
2012-01-13 03:57:21

[ Watch the Video ] UCSF Gallo scientists show that drinking releases brain endorphins Drinking alcohol leads to the release of endorphins in areas of the brain that produce feelings of pleasure and reward, according to a study led by researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco. The finding marks the first time that endorphin release in the nucleus accumbens and orbitofrontal cortex in response to alcohol consumption has...

2011-10-13 11:50:22

Itching is one of the most prevalent side effects of powerful, pain-killing drugs like morphine, oxycodone and other opioids. The opiate-associated itch is so common that even women who get epidurals for labor pain often complain of itching. For many years, scientists have scratched their own heads about why drugs that so effectively suppress pain also induce itch. Now in mice, researchers at Washington University School of Medicine in St. Louis have shown they can control opioid-induced...

2011-03-16 23:48:43

Results from a new study suggest that one of the most prescribed medications for alcohol dependence may be more effective in some people. Preliminary results show that naltrexone (Revia), one of the only medications approved for treating people with alcohol abuse problems, may only be effective in women and those with a specific genetic variation. The new study, conducted by researchers from the Research Institute of the McGill University Health Centre (RI MUHC) and McGill University, will be...

2011-03-15 20:59:30

    * Naltrexone is one of the most effective pharmacological treatments for alcohol dependence.    * However, naltrexone does not work for everyone.    * A new study has found that naltrexone is effective for women, and individuals with the A118G polymorphism of the mu opioid receptor gene (OPRM1). There are few pharmacological treatments for alcohol dependence (AD). An opioid receptor antagonist called naltrexone is one of the most effective,...

2009-08-18 23:17:47

A gene linked with physical pain sensitivity is associated with social pain sensitivity as well, U.S. researchers found. Study co-author Naomi Eisenberger of the University of California, Los Angeles, said people with a rare form of the mu-opioid receptor gene -- OPRM1 -- are more sensitive to social rejection and experience more brain evidence of distress in response to rejection than those with the more common form. The study, published online ahead of print in the Proceedings of the...

Word of the Day
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.