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Latest Multiple drug resistance Stories

2012-06-11 10:24:04

Apramycin, already used in animals, shows promise against drug-resistant TB and other "superbugs", without hearing loss ANN ARBOR, Mich., June 11, 2012 /PRNewswire-USNewswire/ -- The world needs new antibiotics to overcome the ever-increasing resistance of disease-causing bacteria - but it doesn't need the side effect that comes with some of the most powerful ones now available: hearing loss. Today, researchers report they have developed a new approach to designing antibiotics that kill...

2012-06-04 09:52:42

Prisoners used ointments as lip balm and for shaving Prisoners need education on the appropriate use of topical antibiotic products, according to a study released today at the 39th Annual Educational Conference and International Meeting of the Association for Professionals in Infection Control and Epidemiology (APIC). The first study to report on the widespread misuse of topical antibiotics among inmates entering prisons from other correctional facilities found that, among inmates who...

2012-05-22 22:21:01

HAYWARD, Calif., and SHANGHAI, May 23, 2012 /PRNewswire/ -- MicuRx Pharmaceuticals, Inc., a privately-held biopharmaceutical company developing next-generation antibiotics, today announced that the U.S. Patent and Trademark Office (USPTO) issued a composition of matter patent covering its clinical candidate, MRX-I. MRX-I is a novel antibacterial oxazolidinone that targets infections due to multi-drug resistant Gram-positive pathogens. "This patent is expected to be the first of a series to...

2012-05-17 09:36:22

Multidrug-resistant pathogens are becoming more frequent, and the few "last resort" treatments available for infections with these bacteria have also shown an increase in use in recent years, according to a study published May 16 in the open access journal PLoS ONE. The authors, led by Makoto Jones of the Veterans Affairs Salt Lake City Health Care System, investigated the use of two such antibiotics, polymyxins and tigecycline, in 127 Veterans Affairs medical centers between 2005 and...

2012-03-28 10:52:40

Combining common antibiotics with additional compounds could make previously resistant bacteria more susceptible to the same antibiotics. 'Resuscitation' of existing antibiotics has the potential to make infections caused by multidrug-resistant bacteria easier to control, reducing antibiotic usage and levels of antimicrobial resistance, say scientists presenting their work at the Society for General Microbiology's Spring Conference in Dublin this week. Researchers from University College...

2011-12-22 07:00:00

SOUTH PLAINFIELD, N.J., Dec. 22, 2011 /PRNewswire/ -- PTC Therapeutics, Inc. (PTC) today announced the receipt of a $5 million Seeding Drug Discovery (SDD) Award from the Wellcome Trust to support the development of small-molecule drugs that target life-threatening infections caused by multidrug-resistant (MDR) Gram-negative bacteria. PTC previously received a $5.4 million SDD Award from the Wellcome Trust to support its BMI1 oncology program. (Logo:...

2011-12-09 16:15:12

Shahriar Mobashery, a University of Notre Dame researcher, is one of the coauthors of a new paper by a group of the world's leading scientists in academia and industry that calls for strong steps to be taken to control the global crisis of antibiotic resistance in bacteria. The group issued a priority list of steps that need to be taken on a global scale to resolve the crisis. The paper is an outgrowth of a meeting the group held at the Banbury Conference Centre in Cold Spring Harbor,...

2011-11-29 10:48:46

A study to be published in the online journal mBio® on November 29 shows that adding antibiotics to swine feed causes microorganisms in the guts of these animals to start sharing genes that could spread antibiotic resistance. Livestock farms use antibiotic drugs regularly, and not just for curing sick animals. Antimicrobial drugs are used as feed additives to boost animal growth, a profitable but controversial practice that is now banned in the European Union and under scrutiny here in...

2011-11-18 03:57:16

Interfering with the ability of biofilm-forming bacteria to sense starvation increases their susceptibility to antibiotics Many infections, even those caused by antibiotic-sensitive bacteria, resist treatment. This paradox has vexed physicians for decades, and makes some infections impossible to cure. A key cause of this resistance is that bacteria become starved for nutrients during infection. Starved bacteria resist killing by nearly every type of antibiotic, even ones they have never...

2011-11-16 08:00:00

MONTREAL, Nov. 16, 2011 /PRNewswire/ - Sunshine Biopharma Inc. (OTCBB: SBFM) a development stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has successfully completed the preclinical studies for Adva-27a, the Company's lead oncology drug candidate.  Adva-27a was found to have unique pharmaceutical properties of substantial clinical interest.  In summary, the...