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Latest Mutation Stories

2012-10-11 12:57:01

Experimental studies of ancestral visual pigments and their mutational variants cast doubt on simplifying assumptions widely used in evolutionary studies of proteins A key assumption that biologists have relied on widely over the past quarter-century in studying the evolution of protein molecules is "highly questionable," according to an article published in the November issue of BioScience. The article, by Shozo Yokoyama, a vision researcher at Emory University, summarizes experimental...

Chaperone Protein Subverts Removal Of Glaucoma-causing Protein
2012-10-09 15:53:46

Inhibiting the protein, Grp94, could offer new treatment for the sight-robbing eye disease The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study led by researchers at the University of South Florida has found. Using a cell model, the researchers also demonstrated that a new specific inhibitor of Grp94 facilitates clearance of the genetically-defective protein, called myocilin, from cells. Reported online...

2012-10-04 10:35:06

Milk consumption has been linked to improved health, with decreased risks of diabetes, metabolic syndrome, and colon cancer. A group of scientists in Sweden found that lactoferricin4-14 (Lfcin4-14), a milk protein with known health effects, significantly reduces the growth rate of colon cancer cells over time by prolonging the period of the cell cycle before chromosomes are replicated. In a new study, investigators report that treatment with Lfcin4-14 reduced DNA damage in colon cancer cells...

2012-09-17 14:12:31

A Chinese research team, led by Anhui Medical University and BGI, has found the strong genetic evidences of mevalonate kinase gene (MVK) mutations link to disseminated superficial actinic porokeratosis (DSAP). It is a major step toward discovering the genetic pathogenesis of DSAP, and sheds an eye-opening insight into its further molecular diagnosis and treatment. The latest study was published online in Nature Genetics. DSAP is a rare, non-cancerous, non-contagious skin disorder that...

2012-09-14 15:24:41

Huntington's gene mutation carriers: Severity of the genetic mutation related to learning efficiency People who bear the genetic mutation for Huntington's disease learn faster than healthy people. The more pronounced the mutation was, the more quickly they learned. This is reported by researchers from the Ruhr-Universität Bochum and from Dortmund in the journal Current Biology. The team has thus demonstrated for the first time that neurodegenerative diseases can go hand in...

2012-09-10 14:45:32

An international team of scientists have shown at an unprecedented level of detail how cells prioritize the repair of genes containing potentially dangerous damage. The research, published in the journal Nature and involving academics from the University of Bristol, the Institut Jacques-Monod in France and Rockefeller University in the US, studied the action of individual molecules in order to understand how cellular repair pathways are triggered. The genetic information that forms the...

2012-09-07 09:51:49

Researchers from the Guy Rouleau Laboratory affiliated with the CHUM Research Centre and the CHU—Sainte-Justine Research Centre have discovered the genetic cause of a rare disease reported only in patients originating from Newfoundland: hereditary spastic ataxia (HSA). This condition is characterized by lower-limb spasticity (or stiffness) and ataxia (lack of coordination), the latter leading to speech and swallowing problems, and eye movement abnormalities. The disease is not...

Autism Risk Increased For Kids Of Older Dads
2012-08-23 10:20:18

Connie K. Ho for redOrbit.com — Your Universe Online Researchers from deCODE Genetics, an Icelandic firm, recently discovered that a father´s age is connected to an increased risk of autism and schizophrenia. The study states that random mutations can become more prevalent with increased paternal age. According to Bloomberg Businessweek, it is the first report by scientists that quantifies the effect of the disorders. The findings were published recently in the online edition...

2012-08-20 15:38:10

In a discovery that defies the popular meaning of the word "wire," scientists have found that Mother Nature uses DNA as a wire to detect the constantly occurring genetic damage and mistakes that “• if left unrepaired “• can result in diseases like cancer and underpin the physical and mental decline of aging. That topic “• DNA wires and their potential use in identifying people at risk for certain diseases “• is the focus of a plenary talk here...


Word of the Day
reremouse
  • A bat.
The word 'reremouse' comes from Middle English reremous, from Old English hrēremūs, hrērmūs ("bat"), equivalent to rear (“to move, shake, stir”) +‎ mouse.
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