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Latest Mutation Stories

2012-01-23 11:19:51

Analyzing all the genes of dozens of people suffering from a rare form of hypertension, Yale University researchers have discovered a new mechanism that regulates the blood pressure of all humans. The findings by an international research team headed by Yale scientists, published online Jan. 22 in the journal Nature, may help explain what goes wrong in the one billion people who suffer from high blood pressure. The study also demonstrates the power of new DNA sequencing methods to find...

2012-01-19 13:50:35

Inherited mutation links exploding chromosomes to cancer An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University Hospital, all in Heidelberg, Germany, have discovered. Their study, published online today in Cell, also presents the first whole genome sequence...

2012-01-12 11:32:45

After a 20-year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the disease. A report on the discovery was published in the January 12, 2012 issue of the New England Journal of Medicine. UNC-Chapel Hill scientist Ethan Lange, PhD, was part of the team of investigators at the Johns Hopkins University School of Medicine, the University of...

2011-12-28 07:48:27

Oxidative stress is the cause of many serious diseases such as cancer, Alzheimer's, arteriosclerosis and diabetes. It occurs when the body is exposed to excessive amounts of electrically charged, aggressive oxygen compounds. These are normally produced during breathing and other metabolic processes, but also in the case of ongoing stress, exposure to UV light or X-rays. If the oxidative stress is too high, it overwhelms the body's natural defenses. The aggressive oxygen compounds destroy...

2011-12-26 07:22:05

Biologists use technology to observe individual differences in fruit flies To track what they can't see, pilots look to the green glow of the radar screen. Now biologists monitoring gene expression, individual variation, and disease have a glowing green indicator of their own: Brown University biologists have developed a "radar" for tracking ADAR, a crucial enzyme for editing RNA in the nervous system. The advance gives scientists a way to view when and where ADAR is active in a living...

2011-12-22 07:17:39

Results of a new study from the University of North Carolina at Chapel Hill may help pave the way to a treatment for a neurogenetic disorder often misdiagnosed as cerebral palsy or autism. Known as Angelman syndrome, or AS, its most characteristic feature is the absence or near absence of speech throughout the person's life. Occurring in one in 15,000 live births, other AS characteristics include intellectual and developmental delay, severe intellectual disability, seizures, sleep...

2011-12-21 22:45:31

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, reports that abnormal sequences of DNA known as rare copy number variants, or CNVs, appear to play a significant role in the risk for early onset bipolar disorder. The findings will be published in the Dec. 22 issue of the journal Neuron. CNVs are genomic alterations in which there are too few or too many copies of sections of DNA. Researchers have known that...

2011-12-19 14:16:11

Computer model reveals that spatial structure delays tumor formation Cancer growth normally follows a lengthy period of development. Over the course of time, genetic mutations often accumulate in cells, leading first to pre-cancerous conditions and ultimately to tumor growth. Using a mathematical model, scientists at the Max Planck Institute for Dynamics and Self-Organization in Göttingen, University of Pennsylvania and University of California San Francisco, have now shown...

Image 1 - Close Family Ties Keep Microbial Cheaters In Check
2011-12-17 04:14:20

Experiments on "slime mold" explain why almost all multicellular organisms begin life as a single cell Any multicellular animal, from a blue whale to a human being, poses a special challenge for evolution. Most of the cells in its body will die without reproducing; only a privileged few will pass their genes to the next generation. How could the extreme degree of cooperation required by multicellular existence actually evolve? Why aren't all creatures unicellular individualists...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
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