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Last updated on April 24, 2014 at 21:24 EDT

Latest Mutation Stories

Secret Of Short Stems
2013-11-12 14:21:25

Max Planck Institute Arabidopsis plants that only reach half their normal height have a mutation in the biosynthesis of the plant growth factor gibberellin The normal height to which plants grow is a critical trait. In the wild Arabidopsis thaliana uses the same genetic changes in the biosynthesis of the growth factor gibberellin to cut its size in half as found in semi-dwarf varieties of rice and barley that have been bred by people. When expressing the same phenotype, various plant...

Bitter Taste Gene May Have Been Beneficial To Human Evolution
2013-11-12 13:31:37

Brett Smith for redOrbit.com - Your Universe Online It can be puzzling sometimes when someone else finds the taste of your favorite food to be disgusting, but research has shown we all perceive the taste of various compounds differently. A new study from researchers at the University of Pennsylvania has found a genetic mutation making certain people more sensitive to the taste of a bitter compound could have been beneficial for certain human populations in Africa, resulting in the...

2013-10-23 04:23:16

GHENT, Belgium, October 23, 2013 /PRNewswire/ -- In a bioinformatics breakthrough, iMinds - STADIUS - KU Leuvenresearchershave successfully applied advanced artificial intelligence to enable the automated analysis of huge amounts of genetic data. Their new software suite, eXtasy, automatically generatesthe most likely cause of a given genetic disorder. The breakthrough directly impacts the treatment of millions of people with a hereditary disease. At least 5% of the...

2013-10-18 13:25:21

Every case of cancer originates from changes in a person's genetic material (mutations). These usually occur as "somatic mutations" in individual cells during an individual's lifetime, rather than being inherited from a person's parents. "Over time, the original damaged cell accumulates additional mutations, and it is still largely unknown why," says Prof. Roland Eils, who leads bioinformatics departments both at DKFZ and Heidelberg University. By studying when and where mutations occur...

2013-10-17 11:45:51

Discovery could help target clinical studies involving Alzheimer's therapeutics People who carry a genetic mutation associated with Alzheimer's disease may develop the disease three years earlier than expected, according to a new study from Keck Medicine of the University of Southern California (USC). Scientists at the Keck School of Medicine of USC have mapped the effects of that genetic mutation, showing for the first time how the Alzheimer's risk factor affects the living human...

Rare Gene Mutation Identified That Sheds Light On Protein's Role In Brain Development
2013-10-16 16:43:32

Duke University Medical Center Though worlds apart, four unrelated families have been united in a medical mystery over the source of a rare inherited disorder that results in their children being born with abnormal brain growth and severe functional impairments. An international team of scientists, led by genetic researchers at Duke Medicine, has solved the case by identifying a recessive gene mutation that reduces the abundance of a certain protein that previously had not been known to...

2013-10-14 11:18:08

Researchers identify key proteins that help establish cell function Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off. Writing in the October 13, 2013 Advance Online Publication of Nature, the scientists say their approach could make it quicker and easier to identify specific gene mutations associated with...

Genetic Variation Fuels Testicular Cancer
2013-10-11 04:33:32

Brett Smith for redOrbit.com - Your Universe Online Using a genomic analysis, a team of international researchers has identified a specific mutation responsible for a dramatic increase in the risk for testicular cancer. The mutation is a single-base change to the genetic code that affects the activity of the p53 protein that is responsible for regulating the activity of a large number of genes, including those responsible for protection from UV rays – according to the team’s report...

2013-10-08 13:50:38

The unique genomic signature could serve as a research model for founding events Researchers at the Sainte-Justine University Hospital Center and University of Montreal have discovered that the genomic signature inherited by today's 6 million French Canadians from the first 8,500 French settlers who colonized New France some 400 years ago has gone through an unparalleled change in human history, in a remarkably short timescale. This unique signature could serve as an ideal model to study...

2013-10-08 10:38:51

Researchers develop a first-of-its-kind mathematical model for the biological process that keeps your immune system working Scientists at USC have created a mathematical model that explains and predicts the biological process that creates antibody diversity – the phenomenon that keeps us healthy by generating robust immune systems through hypermutation. The work is a collaboration between Myron Goodman, professor of biological sciences and chemistry at the USC Dornsife College of...