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Latest Mutation Stories

2013-08-26 11:55:31

Concealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many others are associated with diseases and disease susceptibility. Reed Cartwright, a researcher at Arizona State University's Biodesign Institute, along with colleagues at ASU, Washington University and the Wellcome Trust Sanger Institute, Cambridge, UK, report on a new software tool known as...

Scientists Discover Aneuploidy In Single-celled Organisms
2013-08-14 14:57:39

University of Luxembourg Baker's yeast is a popular test organism in biology. Yeasts are able to duplicate single chromosomes reversibly and thereby adapt flexibly to environmental conditions. Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg, in collaboration with colleagues from the US Institute for Systems Biology (ISB) in Seattle, have now systematically studied the genetics of this process, which biologists refer to as aneuploidy. The...

2013-08-02 12:30:50

Two women have the same genetic mutation – an abnormal BRCA1 gene that puts them both at much higher-than-average risk for breast cancer – but only one woman develops the disease. Why? Michigan State University genetic scientists have begun to understand the mechanisms behind the phenomena. "It's been known for a while that genetic mutations can modify each other," explained Ian Dworkin, MSU associate professor of zoology. "And we also know that the...

DNA Detection Breakthrough Could Lead To Improved Tuberculosis Treatments
2013-07-29 13:22:02

Brett Smith for redOrbit.com - Your Universe Online Minor mutations in DNA code can make for major malfunctions, and a breakthrough technique has allowed scientists to spot genetic changes with greater precision than ever. According to a new report in the journal Nature Chemistry, the new method can look at a specific DNA sequence and pull out a single mutation. "We've really improved on previous approaches because our solution doesn't require any complicated reactions or added...

Genetic Hitchhikers Picked Up By Evolution
2013-07-23 11:01:42

Princeton University In a twist on "survival of the fittest," researchers have discovered that evolution is driven not by a single beneficial mutation but rather by a group of mutations, including ones called "genetic hitchhikers" that are simply along for the ride. These hitchhikers are mutations that do not appear to have a role in contributing to an organism's fitness and therefore its evolution, yet may play an important role down the road. Researchers from Princeton University...

2013-07-15 13:12:28

A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings suggest that these naturally produced mutations are just as powerful as known cancer-causing agents in producing tumors. The proteins are part of a group called apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) cytidine deaminases. The investigators found that APOBEC...

Self-fertilizing Plants Play Part In Their Own Death
2013-06-10 10:28:56

University of Toronto Many plants are self-fertilizing, meaning they act as both mother and father to their own seeds. This strategy — known as selfing — guarantees reproduction but, over time, leads to reduced diversity and the accumulation of harmful mutations. A new study published in the scientific journal Nature Genetics shows that these negative consequences are apparent across a selfing plant's genome, and can arise more rapidly than previously thought. In the study,...

Evolutionary History Of Cancer-related Gene Tracked By CNIO Study
2013-06-06 20:59:35

Centro Nacional de Investigaciones Oncologicas (CNIO) The study reveals how a genetic duplication that occurred millions of years ago encouraged the evolution of the ASF1b gene, involved in cancer development How and when evolution generates diversity or gives form to proteins, living beings' functional building blocks, are essential questions that still surround the theory of evolution. In humans, the majority of genes have emerged via genetic duplication, a strategy in which a gene...

2013-06-06 18:27:15

Genetic mutation of a testis stem cell actually gives the disease an edge, making older fathers more likely to pass it along to their children Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan Syndrome are so common: a mutation that causes the disease disproportionately increases a normal father´s production of sperm carrying the disease trait. When this Noonan syndrome mutation arises in a normal sperm stem cell it makes that cell more...

2013-06-04 23:30:00

In light of Angelina Jolie's recent mastectomy, Kwiksure examines the relationship between health insurance coverage and preventative cancer surgery. Hong Kong (PRWEB) June 04, 2013 Angelina Jolie made headline news recently as she publicly shared her elective preventative double mastectomy in the New York Times on the 14th of May, after testing positive for the BRCA mutation. A week later, a British businessman followed suit with the removal of his healthy prostate as tests showed he also...


Word of the Day
toccata
  • In music, a work for a keyboard-instrument, like the pianoforte or organ, originally intended to utilize and display varieties of touch: but the term has been extended so as to include many irregular works, similar to the prelude, the fantasia, and the improvisation.
This word is Italian in origin, coming from the feminine past participle of 'toccare,' to touch.
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