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Latest Mycobacterium tuberculosis Stories

2012-06-08 05:20:54

(Ivanhoe Newswire) -- In 2010 the World Health Organization (WHO) estimated there were 290,000 cases of multi-drug resistant tuberculosis globally. Now a new medication attempts to slash those numbers. Delamanid, a nitro-dihydro-imidazooxazole derivative, is a new medication that inhibits mycolic acid synthesis (long fatty acids found in the cell walls of the mycolata taxon) and has shown potent in vitro (half living-in a Petri dish) and in vivo (living in the body) activity against drug...

2012-05-18 11:18:59

A tiny filter could have a big impact around the world in the fight against tuberculosis. Using the traditional microscope-based diagnosis method as a starting point, a University of Florida lung disease specialist and colleagues in Brazil have devised a way to detect more cases of the bacterial infection. "We're hopeful that this more sensitive method, which is both simple and inexpensive, will improve diagnosis in patients," said lead researcher Kevin Fennelly, M.D., M.P.H., an associate...

2012-02-15 21:39:34

According to the World Health Organization (WHO), one-third of the world's population is currently infected with tuberculosis bacteria. The bacteria is incredibly resistant to treatment, and despite its prevalence, very little is known about why it is so stress tolerant. But, researchers at the University of Pittsburgh have been developing a new way of culturing tuberculosis bacteria, which could lead to new insights and treatments. "This is a significant step forward in TB research," said...

2011-11-14 23:39:49

The stealth art of infectious agents: Researchers uncover why the body can't defend against tuberculosis Tuberculosis, which kills over 2 million people each year, is caused primarily by infectious bacteria known as Mycobacterium tuberculosis — or Mtb. Mtb targets human immune cells as part of its strategy to avoid detection, effectively neutralizing the body's immune response. Up until now, scientists had a general understanding of the process, but researchers in the Immunity and...

2011-10-18 10:05:44

Research shows connection between development of new lymphoid tissue within the lung and protection against tuberculosis New research from the Trudeau Institute may help in the ongoing fight against tuberculosis. Dr. Andrea Cooper's lab has discovered a connection between the development of new lymphoid tissue within the lung and protection against the disease. The new data will be published in the November 1 print issue of The Journal of Immunology (Vol. 187, Num. 10) and is available now...

2011-10-04 09:27:14

The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body´s defense. New research suggests this represents a novel mechanism in the microbe´s evolving efforts to remain hidden from the human immune system. Researchers found that the TB bacterium has a molecule on its outer surface called lipomannan that can stop production of an important protein in the body´s immune cells that helps contain TB infection and...

2011-08-01 16:03:14

New research published in the Journal of Leukocyte Biology suggests that lack of expression of innate immune system receptor may play a critical role in the immune response to mycobacterial infections Are you genetically predisposed to tuberculosis? Scientists may now be able to answer this question and doctors may be able to adjust their therapeutic approach based on what they learn. That's because new research presented in the Journal of Leukocyte Biology (http://www.jleukbio.org) suggests...

2011-07-27 12:38:59

Press release from PLoS Medicine Two research studies in this week's PLoS Medicine suggest that a new automated DNA test for tuberculosis (Xpert MTB/RIF), which can detect TB within 2 hours and has been endorsed by the World Health Organization, can significantly increase TB detection rate compared to other tests, particularly in HIV positive patients who have a high risk of being infected with TB, including multidrug resistant TB. An accompanying Essay and Perspective highlight the economic...

2011-04-12 14:32:44

The discovery of two genes that encode copper- and sulfur-binding repressors in the hospital terror Staphylococcus aureus means two new potential avenues for controlling the increasingly drug-resistant bacterium, scientists say in the April 15, 2011 issue of the Journal of Biological Chemistry. "We need to come up with new targets for antibacterial agents," said Indiana University Bloomington biochemist David Giedroc, who led the project. "Staph is becoming more and more multi-drug resistant,...

2011-02-10 19:36:56

The realization of medically treating different children uniquely may start with one of the deadliest diseases in existence: tuberculosis. New findings by UT Southwestern Medical Center researchers indicate that the type of medications and the dosage routinely used to treat children with the disease should be individualized to each young patient in order to be effective. The findings, available online and in the February issue of Antimicrobial Agents and Chemotherapy, show that currently...


Latest Mycobacterium tuberculosis Reference Libraries

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2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

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Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin