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Latest Mycobacterium tuberculosis Stories

2008-08-30 09:00:20

By Jarzembowski, Jason A Young, Michael B * Context.-Nontuberculous mycobacteria include numerous acid- fast bacilli species, many of which have only recently been recognized as pathogenic. The diagnosis of mycobacterial disease is based on a combination of clinical features, microbiologic data, radiographic findings, and histopathologic studies. Objective.-To provide an overview of the clinical and pathologic aspects of nontuberculous mycobacteria infection, including diagnostic laboratory...

2008-08-26 03:00:17

By Rajavelu, Priya Das, Sulochana D Background & objectives: Activation of T cells is mediated through two critical signals provided by activated macrophages. The first signal is triggered when T cell receptor (TCR) binds to the major histocompatibility antigen (MHC/Ag) complex. The second signal is the interaction of co-stimulatory molecules with their respective ligands on T cells for their activation and proliferation. We undertook this study to observe the modulation in B7.1 (CD80)...

2008-07-15 12:00:15

By Buff, Ann M Deshpande, Swati J; Harrington, Theresa A; Wofford, Taylor S; O'Hara, Timothy W; Carrigan, Kenichi; Martin, Nicholas J; McDowell, Jackie C; Ijaz, Kashef; Jensen, Paul A; Lambert, Lauren A; Moore, Marisa; Oeltmann, John E ABSTRACT Pulmonary tuberculosis (TB) was diagnosed in a sailor aboard the U.S.S. Ronald Reagan; an investigation was conducted to determine a screening strategy for 1,172 civilian passengers who were aboard during a temporary guest rider program. Sailors were...

2008-07-02 06:00:14

By DeRiemer, Kathryn De Jong, Bouke C The estimated 9.2 million new cases of tuberculosis (TB) and 1.7 million annual deaths from TB during 2006 are a bleak reminder that new, creative strategies are needed to prevent and controlTB worldwide (1). For the past 15 years, molecular epidemiologic techniques have been used to identify clusters of TB cases whose isolates have identicalDNAfingerprints or genotypes, indicating recent transmission of Mycobacterium tuberculosis (2). In this issue of...

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2008-06-11 09:35:51

Growth of TB bacteria as biofilms result in cells genetically and physiologically different from those lab-cultured for antibioticsUniversity of Pittsburgh-led researchers discovered that the primary bacteria behind tuberculosis can grow on surfaces and that drug-tolerant strains flourish in these bacterial communities, the research team recently reported in "Molecular Microbiology." The findings suggest a possible reason why human tuberculosis (TB) requires months of intensive antibiotic...

2007-11-09 06:00:14

By Veeser, Peggy Ingram Smith, Phillip Karl; Handy, Barry; Martin, Sharon R Abstract. Detecting and managing Mycobacterium tuberculosis (TB) infection in a health-science center population is a clinical dilemma. Tuberculin skin tests are still the preferred method for detecting present or past infection of TB. The authors discuss the performance of whole blood interferon gamma release assay test commercially known as QuantiFERON-TB Gold Test (QFT-G) as an additional tool for a TB...

2007-10-09 03:00:07

By Gupta, Nupur Arora, Manju; Singh, Neeta; Dadhwal, Vatsla; Et al Abstract Introduction: Pelvic abscesses still remain a diagnostic and therapeutic challenge for the obstetrician and gynaecologist. Tubo ovarian abscesses (TOAS) are responsible for 1.6 2.2% of all gynaecological admissions in public urban hospitals. Case Report: Out of six cases (mean age 28.1 years) who presented with this condition, two were following hysterosalpingography, one following oocyte retrieval for in vitro...

2005-09-27 14:13:04

St. Petersburg, Russia "“ Genghis Khan and his troops may have unwittingly used more than just brute military force to conquer entire nations and to establish the infamous Mongolian empire. A report in the October issue of Genome Research suggests that Genghis Khan's invasions spanning the continent of Asia during the 13th century may have been a primary vehicle for the dissemination of one of the world's most deadly diseases: tuberculosis. In this study, a team of scientists led by Dr....

2005-07-14 16:45:00

Dr. Robert Husson and colleagues have found two serine threonine kinase genes (pknA and pknB) that regulate cell shape, and possibly cell division, in the bacterial pathogen, Mycobacterium tuberculosis. The researchers identified three in vivo substrates of PknA and PknB, one of which (Wag31) is an important factor in controlling bacterial cell division and cell shape. Overexpression of either Pkn protein results in a cell shape defect. Dr. Husson is confident that "these findings describe a...

2004-11-25 03:00:16

Tuberculosis is a major health problem throughout the world causing large number of deaths, more than that from any other single infectious disease. The review attempts to summarize the information available on host immune response to Mycobacterium tuberculosis. Since the main route of entry of the causative agent is the respiratory route, alveolar macrophages are the important cell types, which combat the pathogen. Various aspects of macrophage- mycobacteriiim interactions and the role of...


Latest Mycobacterium tuberculosis Reference Libraries

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2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

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Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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