Quantcast

Latest Mycobacterium Stories

2011-12-15 17:17:47

Findings could lead to more effective treatment for global disease A new study led by Harvard School of Public (HSPH) researchers provides a novel explanation as to why some tuberculosis cells are inherently more difficult to treat with antibiotics. The discovery, which showed that the ways mycobacteria cells divide and grow determine their susceptibility to treatment with drugs, could lead to new avenues of drug development that better target tuberculosis cells. The study appears...

2011-12-02 01:46:06

The World Health Organization estimates that one-third of the world's population is currently infected with the microbe that causes tuberculosis, Mycobacterium tuberculosis. The only vaccine, BCG, is largely ineffective; ways to enhance its effectiveness are desperately needed. A team of researchers – led by Peter Andersen, at Statens Serum Institut, Denmark, and JoAnne L. Flynn, at the University of Pittsburgh School of Medicine, Pittsburgh, – has now developed a vaccine that...

2011-11-16 23:37:14

It's estimated that nearly one-third of the world's population–more than two billion people–are infected with Mycobacterium tuberculosis. According to the World Health Organization, 5 to 10 percent of infected people eventually develop active tuberculosis and can transmit the bacterium to others. Almost two million die from the disease each year. But the current treatment regimen for the disease is long and arduous, making patient compliance difficult. As a result, some strains of...

2011-10-04 09:27:14

The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body´s defense. New research suggests this represents a novel mechanism in the microbe´s evolving efforts to remain hidden from the human immune system. Researchers found that the TB bacterium has a molecule on its outer surface called lipomannan that can stop production of an important protein in the body´s immune cells that helps contain TB infection and...

2011-09-08 10:14:31

(Ivanhoe Newswire) — A potential vaccine against tuberculosis (TB) has been found to completely eliminate TB bacteria from infected tissues in some mice. The vaccine was made from a strain of bacteria that are unable to avoid its host´s first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that remembers the bacteria and protects against future infection. Tuberculosis, an infectious disease caused by...

2011-09-06 12:45:41

  An experimental vaccine composed of a genetically modified bacterium closely related to the bacterium that causes tuberculosis (TB) has been found to protect mice against TB infection, according to a study appearing online September 4 in the journal Nature Medicine. The research was funded in part by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health. TB, a respiratory disease that according to World Health Organization estimates...

2011-09-05 11:16:45

A potential vaccine against tuberculosis has been found to completely eliminate tuberculosis bacteria from infected tissues in some mice. The vaccine was created with a strain of bacteria that, due to the absence of a few genes, are unable to avoid its host's first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that can protect against future infections. The research, by scientists at the Howard Hughes Medical Institute,...

TB Vaccine Shows Promising Results In Lab Tests
2011-09-05 04:48:52

  Scientists at the Albert Einstein College of Medicine reported on Sunday that a vaccine they developed for tuberculosis had shown promising results during early laboratory testing in mice. Professor William Jacobs and colleagues, who published their findings in the journal Nature Medicine on Sunday, worked with Mycobacterium smegmatis, a species similar to tuberculosis that is lethal in mice but harmless to humans. "The researchers created a version of M. smegmatis lacking a...


Latest Mycobacterium Reference Libraries

72_0ab04c9452ae9b3c6ae51f6deb1bcc35
2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

45_255d6ba67dfe6f32b9c7c31f338bf912
2011-04-18 22:11:24

Mycobacterium bovis is a slow-growing, aerobic bacterium and the causative agent of tuberculosis in cattle. Similar to M. tuberculosis, M. bovis can jump the species barrier and cause tuberculosis in humans. It is estimated that M. bovis was responsible for more losses among farm animals than all other diseases combined in the first half of the 20th century. Infection happens after bacterium is ingested. It is generally transmitted to humans via infected milk. Actual human infections are...

More Articles (2 articles) »
Word of the Day
barghest
  • A goblin in English folklore, often appearing in the shape of a large dog and believed to portend imminent death or misfortune.
  • A ghost, wraith, hobgoblin, elf, or spirit.
The origin of 'barghest' is not known, but it may be from perhaps burh-ghest, town-ghost, or German Berg-geist (mountain spirit) or Bär-geist (bear-spirit).
Related