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Latest Mycobacterium Stories

2011-12-02 01:46:06

The World Health Organization estimates that one-third of the world's population is currently infected with the microbe that causes tuberculosis, Mycobacterium tuberculosis. The only vaccine, BCG, is largely ineffective; ways to enhance its effectiveness are desperately needed. A team of researchers – led by Peter Andersen, at Statens Serum Institut, Denmark, and JoAnne L. Flynn, at the University of Pittsburgh School of Medicine, Pittsburgh, – has now developed a vaccine that...

2011-11-16 23:37:14

It's estimated that nearly one-third of the world's population–more than two billion people–are infected with Mycobacterium tuberculosis. According to the World Health Organization, 5 to 10 percent of infected people eventually develop active tuberculosis and can transmit the bacterium to others. Almost two million die from the disease each year. But the current treatment regimen for the disease is long and arduous, making patient compliance difficult. As a result, some strains of...

2011-10-04 09:27:14

The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body´s defense. New research suggests this represents a novel mechanism in the microbe´s evolving efforts to remain hidden from the human immune system. Researchers found that the TB bacterium has a molecule on its outer surface called lipomannan that can stop production of an important protein in the body´s immune cells that helps contain TB infection and...

2011-09-08 10:14:31

(Ivanhoe Newswire) — A potential vaccine against tuberculosis (TB) has been found to completely eliminate TB bacteria from infected tissues in some mice. The vaccine was made from a strain of bacteria that are unable to avoid its host´s first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that remembers the bacteria and protects against future infection. Tuberculosis, an infectious disease caused by...

2011-09-06 12:45:41

  An experimental vaccine composed of a genetically modified bacterium closely related to the bacterium that causes tuberculosis (TB) has been found to protect mice against TB infection, according to a study appearing online September 4 in the journal Nature Medicine. The research was funded in part by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health. TB, a respiratory disease that according to World Health Organization estimates...

2011-09-05 11:16:45

A potential vaccine against tuberculosis has been found to completely eliminate tuberculosis bacteria from infected tissues in some mice. The vaccine was created with a strain of bacteria that, due to the absence of a few genes, are unable to avoid its host's first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that can protect against future infections. The research, by scientists at the Howard Hughes Medical Institute,...

TB Vaccine Shows Promising Results In Lab Tests
2011-09-05 04:48:52

  Scientists at the Albert Einstein College of Medicine reported on Sunday that a vaccine they developed for tuberculosis had shown promising results during early laboratory testing in mice. Professor William Jacobs and colleagues, who published their findings in the journal Nature Medicine on Sunday, worked with Mycobacterium smegmatis, a species similar to tuberculosis that is lethal in mice but harmless to humans. "The researchers created a version of M. smegmatis lacking a...

2011-08-17 12:19:16

Published in Journal of Applied Microbiology Researchers have discovered a faster, cheaper method for the diagnosis of tuberculosis (TB). A major barrier in TB prevention, especially in developing countries, is that diagnosis is slow and costly. Dr Olivier Braissant and his colleagues have developed a method which could potentially decrease the time taken to make a diagnosis. Their method is also cheaper than the current fastest methods. This research has been published today in the Society...

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2011-08-12 05:37:32

A report published in the September issue of the CDC journal Emerging Infectious Diseases indicates that two men contracted a rare bacterial skin infection from a tattoo parlor in Seattle, WA. This infection is typically found only in immune suppressed individuals. The infection, called Mycobacterium haemophilum, is in the same family as those that cause tuberculosis and leprosy. Researchers indicate that symptoms include small bumps at the site of infection, redness, pain, swelling and...

2011-08-01 16:45:39

Azithromycin is an antibiotic that also has antiinflammatory properties. It is these antiinflammatory properties that are thought to account for the improvement in clinical outcome observed when patients with chronic lung diseases such as cystic fibrosis are treated long-term with azithromycin. However, a recent study indicated that azithromycin treatment in patients with cystic fibrosis is associated with increased infection with nontuberculous mycobacteria, a serious complication in such...


Latest Mycobacterium Reference Libraries

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2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

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2011-04-18 22:11:24

Mycobacterium bovis is a slow-growing, aerobic bacterium and the causative agent of tuberculosis in cattle. Similar to M. tuberculosis, M. bovis can jump the species barrier and cause tuberculosis in humans. It is estimated that M. bovis was responsible for more losses among farm animals than all other diseases combined in the first half of the 20th century. Infection happens after bacterium is ingested. It is generally transmitted to humans via infected milk. Actual human infections are...

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