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Latest Mycobacterium Stories

2010-11-17 13:27:35

A key enzyme in Mycobacterium tuberculosis that enables the microbe to reproduce rapidly could be a golden target for new drugs against tuberculosis (TB), according to a study published in Microbiology on 17 November. The human equivalent of this enzyme has been targeted in some cancer treatments as well as in immunosuppressive chemotherapies. Scientists at the University of Birmingham have now shown that inhibiting the same enzyme in M. tuberculosis effectively kills the bacterial cells. The...

2010-11-08 19:53:17

Researchers at the University of California, San Diego School of Medicine and the University of Leeds have linked hundreds of federally approved drugs to more than 1,000 proteins in Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), opening new avenues to repurpose these drugs to treat TB. The study was published Nov. 4 in PLoS Computational Biology. "Tuberculosis is currently one of the most widely spread infectious diseases, with an estimated one-third of the world's...

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2010-10-01 09:16:53

Kathleen Alexander, associate professor of wildlife in Virginia Tech's College of Natural Resources and Environment, has discovered a novel tuberculosis (TB) species in the Mycobacterium tuberculosis complex, a group of pathogens that have adapted by using mammals as hosts. It has been nearly two decades since a new organism was identified in this group; the majority were discovered in the early and mid 20th century. Tuberculosis is presently the leading cause of death from infectious...

2010-09-17 14:07:02

Computer model finds probable genetic mechanism for TB dormancy An examination of a portion of the tuberculosis genome that responds to stress has allowed Rice University bioengineers Oleg Igoshin and Abhinav Tiwari to zero in on a network of genes that may "switch" the disease into dormancy. The bacteria that cause tuberculosis (TB), Mycobacterium tuberculosis, can transition into a dormant state to ward off attacks from antibiotics and the immune system. A new report from Igoshin and Tiwari...

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2010-08-19 10:25:00

Patients suffering from active tuberculosis (TB) have a specific pattern of genes in their blood, according to a new study from scientists which could lead to better diagnostic tests and improved treatment methods for those suffering from the often deadly infectious disease.The so-called "genetic signature"--discovered by a team of researchers led by Anne O'Garra of the Medical Research Council (MRC)--is present in as many as 10% of the approximately 2 billion people worldwide who are...

2010-07-26 08:20:00

ROCKVILLE, Md., July 26 /PRNewswire/ -- Sequella, Inc., a clinical-stage biopharmaceutical company developing drugs for treatment of life-threatening infectious diseases, announced today the publication of studies in the scientific journal Antimicrobial Agents and Chemotherapy on synergy between SQ109, its lead drug candidate for the treatment of TB, and TMC207, Tibotec lead TB drug candidate: Reddy, V.M., L. Einck, K. Andries, and C.A. Nacy. In Vitro Interactions between New...

2010-07-21 13:23:27

Two tips for preventing Johne's disease on dairy farms: Use stainless steel water troughs and add chlorine to the water. That's according to Kim Cook, an Agricultural Research Service (ARS) microbiologist at the agency's Animal Waste Management Research Unit in Bowling Green, Ky. Cook did the research with Carl Bolster, a hydrologist at Bowling Green, and other colleagues. Stainless steel troughs are expensive, but not as expensive as Johne's disease. Caused by the bacterium Mycobacterium...

2010-06-24 15:37:00

VALENCIA, Calif., June 24 /PRNewswire/ -- Today the United States (U.S.) Centers for Disease Control and Prevention (CDC) issued new and important guidelines on the detection of Mycobacterium tuberculosis infections, the causative agent of tuberculosis (TB). In these landmark guidelines, CDC advises that Interferon Gamma Release Assay (IGRA) blood tests are now preferred over the 100+-year-old tuberculin skin test (TST) for diagnosing TB infection in certain populations, including people...

2010-06-23 13:48:19

Press release from PLoS Medicine A large, systematic postmortem study carried out in South Africa by Ted Cohen and colleagues has revealed that 94% of deceased patients were HIV infected and 50% had culture-positive tuberculosis at the time of death. These data, which reveal that the toll of tuberculosis in young people (age 20-45) in KwaZulu-Natal is higher than we previously thought, are published this week in the open access medical journal PLoS Medicine. Every year, nearly 10 million...

2010-06-18 15:00:32

Buruli ulcers, one of the 'neglected tropical diseases' left aside by big pharma and governments alike, are reasonably well treatable, also in poor regions. But then more attention has to be paid to early diagnosis and correct treatment. This means the rules of the World Health Organization urgently need to be changed. So say scientists of the Antwerp Institute of Tropical Medicine (ITM), based on ten years of research in Congo. The disease is caused by Mycobacterium ulcerans, a nephew of the...


Latest Mycobacterium Reference Libraries

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2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

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2011-04-18 22:11:24

Mycobacterium bovis is a slow-growing, aerobic bacterium and the causative agent of tuberculosis in cattle. Similar to M. tuberculosis, M. bovis can jump the species barrier and cause tuberculosis in humans. It is estimated that M. bovis was responsible for more losses among farm animals than all other diseases combined in the first half of the 20th century. Infection happens after bacterium is ingested. It is generally transmitted to humans via infected milk. Actual human infections are...

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Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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