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Last updated on April 24, 2014 at 14:12 EDT

Latest Myelin Stories

2010-06-09 21:43:44

Discovery underscores difficulties in developing regenerative spinal cord injury therapies Neuroscientists at the University of California, San Diego School of Medicine have found that removing three key inhibitory molecules from myelin "“ the insulating material that surrounds nerve cell fibers "“ does not significantly boost the ability of injured spinal axons to regenerate and restore themselves to full function. "I think this just shows how incredibly complicated the challenge...

2010-06-08 18:06:24

A protein that helps build the brain in infants and children may aid efforts to restore damage from multiple sclerosis (MS) and other neurodegenerative diseases, researchers at Washington University School of Medicine in St. Louis have found. In a mouse model of MS, researchers found that the protein, CXCR4, is essential for repairing myelin, a protective sheath that covers nerve cell branches. MS and other disorders damage myelin, and this damage is linked to loss of the branches inside the...

2010-06-01 19:21:07

A synthetic version of a naturally occurring peptide promoted the creation of new blood vessels and repaired damaged nerve cells in lab animals, according to researchers at Henry Ford Hospital in Detroit. "This successful experiment holds promise for treating clot-induced strokes in humans," says study lead author Daniel C. Morris, M.D., senior staff physician in the Department of Emergency Medicine at Henry Ford Hospital. "Neurorestorative therapy is the next frontier in the treatment of...

2010-04-15 09:03:12

New research investigating neurological decline in a population of "super healthy" elderly subjects found that the decline in neurological function of the peripheral nervous system attributed to aging may be related to metabolic factors, such as blood sugar levels, even if these factors are within the normal range. In a related study of peripheral nerve function, the same group found that aging affects the nerves of men more than women later in life. The findings imply, the researchers say,...

2010-04-15 07:44:35

A UCSF-led study examining the impact of statins on the progression of multiple sclerosis found a lower incidence of new brain lesions in patients taking the cholesterol-lowering drug in the early stages of the disease as compared to a placebo. Study participants received an 80 milligram daily dose of atorvastatin, marketed by Pfizer Inc. as Lipitor. Although the study was small with only 81 participants and its primary endpoint, designed to evaluate MS progression in patients following their...

2010-02-27 08:09:56

A non-pathogenic bacterium is capable to trigger an autoimmune disease similar to the multiple sclerosis in the mouse, the model animal which helps to explain how human diseases work. This is what a group of researchers from the Catholic University of Rome, led by Francesco Ria (Institute of General Pathology) and Giovanni Delogu (Institute of Microbiology), have explained for the first time in a recently published article on the Journal of Immunology. Multiple sclerosis is a disease due to...

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2010-02-24 10:42:41

Researchers at UTHealth have demonstrated in rats that transplanting genetically modified adult stem cells into an injured spinal cord can help restore the electrical pathways associated with movement. The results are published in the Feb. 24 issue of the Journal of Neuroscience. In spinal cord injury, demyelination, or the destruction of the myelin sheath in the central nervous system, occurs. The myelin sheath, produced by cells called oligodendrocytes, wraps around the axons of nerves and...

2010-02-07 09:17:54

Fewer African Americans than Caucasians develop multiple sclerosis (MS), statistics show, but their disease progresses more rapidly, and they don't respond as well to therapies, a new study by neurology researchers at the University at Buffalo has found. Magnetic resonance images (MRI) of a cohort of 567 consecutive MS patients showed that blacks with MS had more damage to brain tissue and had less normal white and gray matter compared to whites with the disease. Results of the study were...

2010-02-02 16:40:36

The cells regarded as the "gate-keepers" of the barrier between blood circulation and the peripheral nerves have been hard to study and even harder to isolate. However, researchers at Baylor College of Medicine have created a laboratory model that will enable scientists to study a wide variety of diseases affecting peripheral nerves. They describe their model in the January 2010 issue of the Journal of Neuropathology and Experimental Neurology. Specialized vascular system "The barrier is...

2010-02-01 18:01:14

Surprise finding may have implications for labor anesthesia, orthopedics and more One of the holy grails of local anesthesia is the ability to achieve a long-lasting nerve block that eliminates pain sensation while not affecting motor function. Now, researchers at Children's Hospital Boston have discovered an anesthetic approach that seems to do just that. If it proves to work in humans as well as it did in rats, it could be useful in a variety of medical applications, providing, for example,...