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Latest Nanopore sequencing Stories

Virus Reveals Physics Of Nanopores
2014-06-17 03:36:51

By Kevin Stacey, Brown University Nanopores may one day lead a revolution in DNA sequencing. By sliding DNA molecules one at a time through tiny holes in a thin membrane, it may be possible to decode long stretches of DNA at lightning speeds. Scientists, however, haven’t quite figured out the physics of how polymer strands like DNA interact with nanopores. Now, with the help of a particular type of virus, researchers from Brown University have shed new light on this nanoscale physics....

Researchers Improve Nanopore-based Technology For Detecting DNA Molecules
2013-11-18 08:34:01

Ecole Polytechnique Fédérale de Lausanne If we wanted to count the number of people in a crowd, we could make on the fly estimates, very likely to be imprecise, or we could ask each person to pass through a turnstile. The latter resembles the model that EPFL researchers have used for creating a "DNA reader" that is able to detect the passage of individual DNA molecules through a tiny hole: a nanopore with integrated graphene transistor. The DNA molecules are diluted in a solution...

Advance In Nanotech Gene Sequencing Technique Made By Penn Research
2013-05-20 14:46:57

University of Pennsylvania The allure of personalized medicine has made new, more efficient ways of sequencing genes a top research priority. One promising technique involves reading DNA bases using changes in electrical current as they are threaded through a nanoscopic hole. Now, a team led by University of Pennsylvania physicists has used solid-state nanopores to differentiate single-stranded DNA molecules containing sequences of a single repeating base. The study was led by Marija...

Genome Sequencing In Minutes - Too Fast To Handle
2012-10-19 04:13:54

Alan McStravick for redOrbit.com - Your Universe Online With the introduction of the idea of nanopore sequencing first being proposed in the mid 1990´s, huge advances have been made in this burgeoning technology. The strength of the idea lies in its simplicity. Nanopore sequencing is derived through the collection of a single thread of DNA which is passed through a tiny molecule-sized hole, or nanopore, allowing for the various DNA bases to be analyzed and identified as they move...

Created by Digital Micrograph, Gatan Inc.
2012-10-03 14:47:27

Less Costly Ways of Sequencing DNA Could Open New Possibilities for Disease Prevention Engineers at The University of Texas at Dallas have used advanced techniques to make the material graphene small enough to read DNA. Shrinking the size of a graphene pore to less than one nanometer — small enough to thread a DNA strand  — opens the possibility of using graphene as a low-cost tool to sequence DNA. “Sequencing DNA at a very cheap cost would enable scientists...

2012-09-24 12:44:56

DNA sequencing is the driving force behind key discoveries in medicine and biology. For instance, the complete sequence of an individual´s genome provides important markers and guidelines for medical diagnostics and healthcare. Up to now, the major roadblock has been the cost and speed of obtaining highly accurate DNA sequences. While numerous advances have been made in the last 10 years, most current high-throughput sequencing instruments depend on optical techniques for the detection...

2012-04-19 12:35:04

2 TUM advances combine for new capabilities in single-molecule sensing The latest advance in solid-state nanopore sensors — devices that are made with standard tools of the semiconductor industry yet can offer single-molecule sensitivity for label-free protein screening — expands their bag of tricks through bionanotechnology. Researchers at the Technische Universitaet Muenchen have enhanced the capabilities of solid-state nanopores by fitting them with cover plates made of DNA....

2012-03-27 01:08:04

Researchers have devised a nanoscale sensor to electronically read the sequence of a single DNA molecule, a technique that is fast and inexpensive and could make DNA sequencing widely available. The technique could lead to affordable personalized medicine, potentially revealing predispositions for afflictions such as cancer, diabetes or addiction. "There is a clear path to a workable, easily produced sequencing platform," said Jens Gundlach, a University of Washington physics professor...


Word of the Day
toccata
  • In music, a work for a keyboard-instrument, like the pianoforte or organ, originally intended to utilize and display varieties of touch: but the term has been extended so as to include many irregular works, similar to the prelude, the fantasia, and the improvisation.
This word is Italian in origin, coming from the feminine past participle of 'toccare,' to touch.
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