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Latest Nanopore Stories

2012-10-03 06:30:20

MOUNTAIN VIEW, Calif., Oct. 3, 2012 /PRNewswire/ -- Genia Technologies, Inc. today announced a collaboration with investigators at Columbia University and Harvard University to develop a nanopore-based sequencing system that will accelerate the use of DNA sequencing in the clinic. The three-way collaboration focuses on the development of a single molecule sequencing system combining Genia's standard complementary metal-oxide semiconductor (CMOS) integrated circuit, Professor George...

2012-09-24 12:44:56

DNA sequencing is the driving force behind key discoveries in medicine and biology. For instance, the complete sequence of an individual´s genome provides important markers and guidelines for medical diagnostics and healthcare. Up to now, the major roadblock has been the cost and speed of obtaining highly accurate DNA sequences. While numerous advances have been made in the last 10 years, most current high-throughput sequencing instruments depend on optical techniques for the detection...

2012-04-19 12:35:04

2 TUM advances combine for new capabilities in single-molecule sensing The latest advance in solid-state nanopore sensors — devices that are made with standard tools of the semiconductor industry yet can offer single-molecule sensitivity for label-free protein screening — expands their bag of tricks through bionanotechnology. Researchers at the Technische Universitaet Muenchen have enhanced the capabilities of solid-state nanopores by fitting them with cover plates made of DNA....

2012-03-27 01:08:04

Researchers have devised a nanoscale sensor to electronically read the sequence of a single DNA molecule, a technique that is fast and inexpensive and could make DNA sequencing widely available. The technique could lead to affordable personalized medicine, potentially revealing predispositions for afflictions such as cancer, diabetes or addiction. "There is a clear path to a workable, easily produced sequencing platform," said Jens Gundlach, a University of Washington physics professor...

Researchers Increase Speed Of Single-molecule Measurements
2012-03-19 04:22:15

New integrated circuit design could lead to cheaper, faster DNA sequencing As nanotechnology becomes ever more ubiquitous, researchers are using it to make medical diagnostics smaller, faster, and cheaper, in order to better diagnose diseases, learn more about inherited traits, and more. But as sensors get smaller, measuring them becomes more difficult–there is always a tradeoff between how long any measurement takes to make and how precise it is. And when a signal is very weak, the...

2012-03-15 22:45:28

'Identity check' selectively screens single molecules passing through nanopores A novel type of sensor, based on nanometer-scale pores in a semiconductor membrane, is a step closer to practical use in applications such as analyzing the protein contents of a single cell. Researchers pioneering single-molecule nanopore sensor technology at the Technische Universität München (TUM) have shown its potential through a succession of experiments over the past few...

2012-01-10 23:21:53

New method for nucleic acid analysis In the world of biomolecules such as proteins and the hereditary nucleic acids DNA and RNA, three-dimensional structure determines function. Analysis of the passage of such molecules through nanopores offers a relatively new, but highly promising, technique for obtaining information about their spatial conformations. However, interactions between the test molecules and the proteins used as pores have so far hindered quantitative analysis of the behavior...

2011-10-11 07:00:00

BRANFORD, Connecticut and TEMPE, Arizona, October 11, 2011 /PRNewswire/ -- Roche (SIX: RO, ROG; OTCQX: RHHBY [http://www.roche.com/investors.htm ]) and Arizona Technology Enterprises (AzTE) announced today an agreement to license several technologies developed by Dr. Stuart Lindsay at the Biodesign Institute at Arizona State University and Dr. Colin Nuckolls of the Columbia University Nanoscience Center for the development of a revolutionary DNA sequencing system. The licensed...

2011-09-15 20:22:55

Nanotechnology sensor could lead to earlier diagnosis for world's deadliest form of cancer When lung cancer strikes, it often spreads silently into more advanced stages before being detected. In a new article published in Nature Nanotechnology, biological engineers and medical scientists at the University of Missouri reveal how their discovery could provide a much earlier warning signal. "Early detection can save lives, but there is currently no proven screening test available for lung...