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Latest Nanopore Stories

Synthetic Membrane Channels Built Out Of DNA
2012-11-21 08:03:43

Technische Universitaet Muenchen Nanotech structures mimic nature's way of tunneling through cell walls As reported in the journal Science, physicists at the Technische Universitaet Muenchen (TUM) and the University of Michigan have shown that synthetic membrane channels can be constructed through "DNA nanotechnology." This technique employs DNA molecules as programmable building materials for custom-designed, self-assembling, nanometer-scale structures. The researchers present evidence...

Genome Sequencing In Minutes - Too Fast To Handle
2012-10-19 04:13:54

Alan McStravick for redOrbit.com - Your Universe Online With the introduction of the idea of nanopore sequencing first being proposed in the mid 1990´s, huge advances have been made in this burgeoning technology. The strength of the idea lies in its simplicity. Nanopore sequencing is derived through the collection of a single thread of DNA which is passed through a tiny molecule-sized hole, or nanopore, allowing for the various DNA bases to be analyzed and identified as they move...

Graphene Membranes Could Lead To Enhanced Natural Gas Production And Reduce CO2 Pollution
2012-10-09 11:37:17

Engineering faculty and students at the University of Colorado Boulder have produced the first experimental results showing that atomically thin graphene membranes with tiny pores can effectively and efficiently separate gas molecules through size-selective sieving. The findings are a significant step toward the realization of more energy-efficient membranes for natural gas production and for reducing carbon dioxide emissions from power plant exhaust pipes. Mechanical engineering...

Created by Digital Micrograph, Gatan Inc.
2012-10-03 14:47:27

Less Costly Ways of Sequencing DNA Could Open New Possibilities for Disease Prevention Engineers at The University of Texas at Dallas have used advanced techniques to make the material graphene small enough to read DNA. Shrinking the size of a graphene pore to less than one nanometer — small enough to thread a DNA strand  — opens the possibility of using graphene as a low-cost tool to sequence DNA. “Sequencing DNA at a very cheap cost would enable scientists...

2012-09-24 12:44:56

DNA sequencing is the driving force behind key discoveries in medicine and biology. For instance, the complete sequence of an individual´s genome provides important markers and guidelines for medical diagnostics and healthcare. Up to now, the major roadblock has been the cost and speed of obtaining highly accurate DNA sequences. While numerous advances have been made in the last 10 years, most current high-throughput sequencing instruments depend on optical techniques for the detection...

2012-04-19 12:35:04

2 TUM advances combine for new capabilities in single-molecule sensing The latest advance in solid-state nanopore sensors — devices that are made with standard tools of the semiconductor industry yet can offer single-molecule sensitivity for label-free protein screening — expands their bag of tricks through bionanotechnology. Researchers at the Technische Universitaet Muenchen have enhanced the capabilities of solid-state nanopores by fitting them with cover plates made of DNA....

2012-03-27 01:08:04

Researchers have devised a nanoscale sensor to electronically read the sequence of a single DNA molecule, a technique that is fast and inexpensive and could make DNA sequencing widely available. The technique could lead to affordable personalized medicine, potentially revealing predispositions for afflictions such as cancer, diabetes or addiction. "There is a clear path to a workable, easily produced sequencing platform," said Jens Gundlach, a University of Washington physics professor...

Researchers Increase Speed Of Single-molecule Measurements
2012-03-19 04:22:15

New integrated circuit design could lead to cheaper, faster DNA sequencing As nanotechnology becomes ever more ubiquitous, researchers are using it to make medical diagnostics smaller, faster, and cheaper, in order to better diagnose diseases, learn more about inherited traits, and more. But as sensors get smaller, measuring them becomes more difficult–there is always a tradeoff between how long any measurement takes to make and how precise it is. And when a signal is very weak, the...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'